Integrated Investigations of Supramolecular Structures and Dynamics

有机和大分子化学项目通过这一更新奖支持哥伦比亚大学化学系Nicholas J. Turro博士的持续研究。拟议的研究包括对各种超分子体系的结构和动力学的合作研究，其中反应性中间体是由紫外线光解产生的。包括在胶束中产生的双自由基对和双自由基，在沸石的内外表面产生的自由基，自由基对和双自由基，以及由DNA与树状大分子相互作用产生的超分子组装。将探讨自旋化学中的对映体选择，包括角动量、旋光性和分子手性之间的可能联系。提出了基础研究，以表征具有不寻常性质的新材料，并阐明小客体分子与生物分子的结合机制。这项工作是跨学科的，在催化、尺寸和形状选择性分离以及材料科学方面具有潜在的应用前景。它将整合研究和教育，积极让哥伦比亚大学的本科生和研究生参与研究项目，并通过使用万维网和其他信息技术进行教学。

With this renewal award the Organic and Macromolecular Chemistry Program supports the continuing research of Dr. Nicholas J. Turro of the Department of Chemistry at Columbia University. The proposed research involves collaborative investigations of the structures and dynamics of a variety of supramolecular systems in which reactive intermediates are generated by uv photolysis. Included are geminate radical pairs and biradicals generated in micelles, radicals, radical pairs, and biradicals generated on the external and internal surfaces of zeolites, and supramolecular assemblies resulting from the interactions of DNA with dendrimers. Enantiomeric selection in spin chemistry will be explored, including possible connections between angular momentum, optical activity, and molecular chirality.Fundamental investigations are proposed to characterize novel materials with unusual properties, and to elucidate mechanisms of binding of small guest molecules to biomolecules. The work is interdisciplinary and has potential applications in catalysis, size and shape selective separations, and materials science. It will integrate research and education by actively involving undergraduate and graduate students at Columbia in research projects coupled to instruction through the use of the world wide web and other information technologies.