Integrated Investigations of Supramolecular Structures and Dynamics

超分子结构和动力学的综合研究

• 批准号: 9812676
• 负责人: Nicholas Turro
• 金额: $ 94.64万
• 依托单位: Columbia University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 2001-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9812676&HistoricalAwards=false
• 关键词: Integrated; Investigations; Supramolecular; Structures; Dynamics

With this renewal award the Organic and Macromolecular Chemistry Program supports the continuing research of Dr. Nicholas J. Turro of the Department of Chemistry at Columbia University. The proposed research involves collaborative investigations of the structures and dynamics of a variety of supramolecular systems in which reactive intermediates are generated by uv photolysis. Included are geminate radical pairs and biradicals generated in micelles, radicals, radical pairs, and biradicals generated on the external and internal surfaces of zeolites, and supramolecular assemblies resulting from the interactions of DNA with dendrimers. Enantiomeric selection in spin chemistry will be explored, including possible connections between angular momentum, optical activity, and molecular chirality.Fundamental investigations are proposed to characterize novel materials with unusual properties, and to elucidate mechanisms of binding of small guest molecules to biomolecules. The work is interdisciplinary and has potential applications in catalysis, size and shape selective separations, and materials science. It will integrate research and education by actively involving undergraduate and graduate students at Columbia in research projects coupled to instruction through the use of the world wide web and other information technologies.

通过这一续展奖项，有机和高分子化学项目支持哥伦比亚大学化学系尼古拉斯·J·特罗博士的继续研究。这项拟议的研究涉及对各种超分子体系的结构和动力学的合作研究，在这些超分子体系中，通过紫外光分解产生活性中间体。包括在胶束中产生的双自由基对和双自由基、在沸石外表面和内表面产生的自由基、自由基对和双自由基，以及DNA与树枝状大分子相互作用产生的超分子组件。我们将探讨自旋化学中对映体的选择，包括角动量、旋光性和分子手性之间的可能联系，并为表征具有特殊性质的新型材料和阐明客体小分子与生物分子的结合机制提供基础研究。这项工作是跨学科的，在催化、尺寸和形状选择性分离以及材料科学方面具有潜在的应用。它将通过使用万维网和其他信息技术，积极让哥伦比亚大学的本科生和研究生参与研究项目，并结合教学，将研究与教育结合起来。