Maintenance of Escherichia coli K-12 Genetic Stock Culture Collection

要求继续为大肠杆菌遗传储存中心的运作提供支助。该中心拥有超过7,500个大肠杆菌K-12菌株的突变衍生品，并在过去五年中分发了大约17,500个经过认证的纯基因培养物。受奖研究人员和教师从事微生物遗传学、分子生物学、重组DNA技术、基因组测序、生物物理学、医学研究和药理学等不同领域的工作。用户可以在学术界、非营利性研究机构、政府和工业实验室找到。该中心也是关于大肠杆菌突变衍生物的基因类型和大肠杆菌基因的功能和遗传图谱的信息来源。它继续协调基因符号的分配，并鼓励遵守公认的遗传命名法。该中心的网站上免费提供大量信息

Continued support is requested for operation of the Escherichia coli Genetic Stock Center. The Center maintains a collection of over 7,500 mutant derivatives of E. coli strain K-12, and has distributed approximately 17,500 certified genetically pure cultures over the last five years. Recipient investigators and teachers work in such diverse fields as microbial genetics, molecular biology, recombinant DNA technology, genome sequencing, biophysics, medical research and pharmacology. Users are found in academia, non-profit research institutes, and government and industrial laboratories. The Center also serves as an information resource on genotypes of mutant derivatives of E. coli and on function and genetic mapping of E. coli genes. It continues to coordinate assignment of gene symbols and to encourage adherence to the accepted genetic nomenclature. Extensive information is made freely available on the Center's Web site