Catalytic Synthesis of Polythioether Macrocycles from Thietanes and Thiiranes

硫杂环丁烷和硫杂丙环催化合成聚硫醚大环化合物

• 批准号: 9909017
• 负责人: Richard Adams
• 金额: $ 36万
• 依托单位: University of South Carolina at Columbia
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-15 至 2003-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9909017&HistoricalAwards=false
• 关键词: Catalytic; Synthesis; Polythioether; Macrocycles; Thietanes

This project explores the synthesis and properties of polythioether macrocycles which have considerable potential use as ligands for transition metal ions. Historically, these molecules have been difficult to make. However, new procedures for synthesizing these molecules have recently been discovered. These procedures center around a metal-catalyzed ring opening reaction of smaller sulfur-containing molecules in which the metal can act as a template for construction of the cycle.With this Award, the Organic and Macromolecular Chemistry Program supports the research of Professor Richard D. Adams of the University of South Carolina. The research project that Professor Adams will conduct under the auspices of this Award involve the creation of molecules that are molecular rings and in which sulfur atoms are placed at regular intervals. Such molecules interact with metals as though they were a crown of thorns, with the sulfur atoms connecting the crown to the metal. In this way the properties of the metal are modified, potentially in such a way that the usefulness of the metal in chemical reactions is enhanced.

本项目探讨了聚硫醚大环的合成及其性能，该大环作为过渡金属离子的配体具有相当大的潜力。从历史上看，这些分子很难制造。然而，最近发现了合成这些分子的新方法。这些过程围绕着金属催化的小含硫分子开环反应展开，其中金属可以作为构建循环的模板。有了这个奖项，有机和大分子化学项目支持南卡罗来纳大学的理查德·d·亚当斯教授的研究。亚当斯教授将在该奖项的支持下进行的研究项目涉及分子环的创造，其中硫原子以一定的间隔放置。这些分子与金属相互作用，就好像它们是一顶荆棘王冠，硫原子将王冠与金属连接起来。通过这种方式，金属的性质得到了改变，从而有可能增强金属在化学反应中的用途。