SGER: Parental Behavior and the Evolution of Disease Resistance

SGER：父母行为和抗病性的进化

• 批准号: 9910464
• 负责人: Marlene Zuk
• 金额: $ 4.03万
• 依托单位: University of California-Riverside
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-01 至 2002-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9910464&HistoricalAwards=false
• 关键词: SGER; Parental; Behavior; Evolution; Disease

This project will examine the evolution of resistance to pathogens and its interface with behavioral phenomena involved in the choice of mates and parental care. The central question asks how differences in selection on males and females has affected the ability to resist disease. Based on differences in the investments made by males and females in providing for offspring theory predicts a trade-off between disease resistance and reproduction. Zuk will investigate the immune responses in field crickets where selection for investments in reproduction as opposed to investments in disease resistance are expected to be more pronounced in males than in females. Zuk predicts that males will be less able to resist disease than females. In vertebrates it widely known that this is the case. This research will pioneer such studies in invertebrates that will therefore allow the development of a research methodology providing the potential to examine these questions in greater depth than previously possible. This research will provide a powerful test of the theoretically predicted differences in the sexes in disease and parasite resistance due, ultimately, to differences in parental investment. It is an important step in understanding the interface between molecular and physiological mechanisms and evolutionary process as mediated by behavior.

这个项目将研究对病原体的抵抗力的进化及其与配偶选择和父母照顾中所涉及的行为现象的界面。 中心问题是，选择对雄性和雌性的差异如何影响抵抗疾病的能力。 根据雄性和雌性在提供后代方面所做投资的差异，理论预测了抗病性和繁殖之间的权衡。 Zuk将研究田野蟋蟀的免疫反应，其中对繁殖投资的选择，而不是对抗病性的投资，预计雄性比雌性更明显。 祖克预测，雄性的抗病能力将低于雌性。 在脊椎动物中，这是众所周知的情况。 这项研究将开创无脊椎动物的此类研究，因此将允许开发一种研究方法，从而有可能比以前更深入地研究这些问题。 这项研究将提供一个强有力的测试理论上预测的性别差异的疾病和寄生虫的抵抗力，最终由于父母的投资的差异。 这是理解分子和生理机制之间的接口和行为介导的进化过程的重要一步。