Sequencing of Chromosome 10 of Rice and Validation of Annotation Methods for Rice

水稻被认为是单子叶植物的模型物种，其中包括玉米、小麦、高粱和大麦等谷物。 水稻的基因组相对较小，是二倍体，易于转化，并且具有易于处理的遗传学和多样化的种质。 除了作为世界大多数人口的主要食物来源之外，这些属性还导致了以获取水稻完整基因组序列为重点的遗传和分子资源的开发。 水稻的完整序列不仅将提供一个基因库来了解水稻的生长和发育，而且还将提供一套分子工具来利用序列信息来研究玉米、小麦和大麦等高度相关的物种，这些物种对基因组方法更难以接受。 该奖项将使总共 31.5 Mb 的水稻基因组序列得以生成并发布到 Genbank。 该序列将使用基因预测程序进行注释，数据库中的相关基因将被识别，并且重复结构和序列将被表征。 此外，还将生成水稻数据与其他植物物种的序列、物理和遗传信息之间的联系。 所有这些工作将与国际水稻基因组计划结合进行。

Rice is considered a model species for monocotyledonous plants, which include cereals such as maize, wheat, sorghum, and barley. Rice has a relatively small genome, is diploid, is readily transformable, and has tractable genetics and a diverse germplasm. These attributes, in addition to its role as a major food source for a majority of the world's population, have resulted in the development of genetic and molecular resources focused on obtaining the complete genome sequence of rice. Not only will the complete sequence of rice provide a reservoir of genes by which to understand rice growth and development, but it will also provide a set of molecular tools to leverage sequence information to highly related species such as maize, wheat and barley, which are more recalcitrant to genomic approaches. This award will enable a total of 31.5 Mb of rice genomic sequence to be generated and released to Genbank. This sequence will be annotated using gene prediction programs, related genes within the database will be identified, and repetitive structures and sequences characterized. In addition, links between rice data and sequence, physical, and genetic information from other plant species will be generated. All of this work will be performed in conjunction with the international rice genome project.