Sequencing of Chromosome 10 of Rice and Validation of Annotation Methods for Rice

水稻被认为是单子叶植物的模式物种，单子叶植物包括玉米、小麦、高粱和大麦等谷物。水稻具有相对较小的基因组，是二倍体，易于转化，具有易于处理的遗传和多样化的种质资源。除了作为世界上大多数人口的主要食物来源的作用外，水稻的这些特性还导致了以获得水稻全基因组序列为重点的遗传和分子资源的开发。水稻的完整序列不仅为了解水稻的生长发育提供了一个基因库，而且还将提供一套分子工具，以利用序列信息来研究玉米、小麦和大麦等高度相关的物种，这些物种对基因组方法更为抗拒。该合同将使总计31.5 Mb的水稻基因组序列得以生成并发布到Genbank。该序列将使用基因预测程序进行注释，识别数据库中的相关基因，并对重复结构和序列进行表征。此外，水稻数据与其他植物物种的序列、物理和遗传信息之间将产生联系。所有这些工作将与国际水稻基因组计划一起进行。

Rice is considered a model species for monocotyledonous plants, which include cereals such as maize, wheat, sorghum, and barley. Rice has a relatively small genome, is diploid, is readily transformable, and has tractable genetics and a diverse germplasm. These attributes, in addition to its role as a major food source for a majority of the world's population, have resulted in the development of genetic and molecular resources focused on obtaining the complete genome sequence of rice. Not only will the complete sequence of rice provide a reservoir of genes by which to understand rice growth and development, but it will also provide a set of molecular tools to leverage sequence information to highly related species such as maize, wheat and barley, which are more recalcitrant to genomic approaches. This award will enable a total of 31.5 Mb of rice genomic sequence to be generated and released to Genbank. This sequence will be annotated using gene prediction programs, related genes within the database will be identified, and repetitive structures and sequences characterized. In addition, links between rice data and sequence, physical, and genetic information from other plant species will be generated. All of this work will be performed in conjunction with the international rice genome project.