Sequencing of Chromosome 10 of Rice and Validation of Annotation Methods for Rice

水稻 10 号染色体测序及水稻注释方法验证

• 批准号: 9983282
• 负责人: Carol Buell
• 金额: $ 460万
• 依托单位: Institute for Genomic Research
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-10-01 至 2004-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9983282&HistoricalAwards=false
• 关键词: Sequencing; Chromosome; 10; Rice; Validation

Rice is considered a model species for monocotyledonous plants, which include cereals such as maize, wheat, sorghum, and barley. Rice has a relatively small genome, is diploid, is readily transformable, and has tractable genetics and a diverse germplasm. These attributes, in addition to its role as a major food source for a majority of the world's population, have resulted in the development of genetic and molecular resources focused on obtaining the complete genome sequence of rice. Not only will the complete sequence of rice provide a reservoir of genes by which to understand rice growth and development, but it will also provide a set of molecular tools to leverage sequence information to highly related species such as maize, wheat and barley, which are more recalcitrant to genomic approaches. This award will enable a total of 31.5 Mb of rice genomic sequence to be generated and released to Genbank. This sequence will be annotated using gene prediction programs, related genes within the database will be identified, and repetitive structures and sequences characterized. In addition, links between rice data and sequence, physical, and genetic information from other plant species will be generated. All of this work will be performed in conjunction with the international rice genome project.

水稻被认为是单子叶植物的模式物种，单子叶植物包括谷物如玉米、小麦、高粱和大麦。 水稻具有相对小的基因组，是二倍体，易于转化，并且具有易处理的遗传学和多样的种质。 这些特性，加上它作为世界大多数人口的主要食物来源的作用，导致了集中于获得水稻完整基因组序列的遗传和分子资源的开发。 水稻的完整序列不仅将提供一个基因库，通过它来了解水稻的生长和发育，而且还将提供一套分子工具，以利用序列信息来研究玉米、小麦和大麦等高度相关的物种，这些物种对基因组方法更不敏感。 该奖项将使总共31.5 Mb的水稻基因组序列得以生成并发布到Genbank。 该序列将使用基因预测程序进行注释，将识别数据库中的相关基因，并表征重复结构和序列。 此外，水稻数据与其他植物物种的序列、物理和遗传信息之间的联系也将产生。 所有这些工作都将与国际水稻基因组计划一起进行。