Metals and Hydrogen Bonding

这一无机化学、生物无机化学和金属有机化学项目的奖项支持密苏里大学圣彼得堡分校化学系李·布拉默的研究。Louis对涉及金属的氢键进行了研究。将涉及三个方面的问题。第一种是金属离子直接参与氢键作用。在这里，我们将研究早期过渡金属作为氢键受体。第二个领域涉及金属通过与能够氢键的配体的电子相互作用而产生的间接影响。研究重点将放在了解超分子结构中通过氢键形成的聚集。最后，我们将研究金属配位几何在指导通过配体-配体氢键连接的金属络合物相互接近中的空间影响。在这一领域，氢键在固态和晶体工程中的作用将被用由配位化合物和有机金属化合物组成的新化合物来研究。最终目标是合理设计固态材料，了解“金属壁”受体和通道的主-客体化学。所合成的化合物将通过溶液和固态光谱、单晶和粉末衍射研究、量热、重量分析和计算模型进行表征。氢键在化学和生物学中很重要，但它在有机金属化学、材料和生物无机化学中的作用尚不清楚，特别是它影响到超分子化学、自组装和晶体工程等新领域。研究将集中在涉及金属的氢键上。传统的研究考虑了非金属元素。这项研究有望更好地理解涉及金属的质子转移反应，新型氢键有机-无机杂化材料，以及涉及有机金属化合物的一类新的主体或通道结构。学生们将在各种实验技术方面获得经验，这些技术在他们寻求新兴化学领域的职业生涯时将是无价的。

This award in the Inorganic, Bioinorganic, and Organometallic Chemistry Program supports research by Lee Brammer, Chemistry Department, University of Missouri-St. Louis, on hydrogen bonds that involve metals. Three aspects will be addressed. The first is the direct involvement of metal ions in hydrogen bonding. Here, early transition metals will be studied as H-bond acceptors. The second area concerns the indirect influence of metals via electronic interaction with ligands capable of hydrogen bonding. Research will focus on understanding aggregation by hydrogen bonding in supramolecular structures. Finally, the spatial influence of metal coordination geometry in directing the mutual approach of metal complexes that are then linked via ligand-ligand hydrogen bonds will be studied. In this domain, the role of hydrogen bonding in solid state and crystal engineering will be investigated using new compounds composed of coordination and organometallic compounds. The ultimate objectives are the rational design of solid state materials and understanding host-guest chemistry of "metal-walled" receptors and channels. The compounds synthesized will be characterized by solution and solid state spectroscopy, single crystal and powder diffraction studies, calorimetry, gravimetric analysis, and computational modeling.Hydrogen bonding is important in chemistry and biology, but its role in organometallic chemistry, materials, and bioinorganic chemistry is not well understood, particularly as it affects new areas such as supramolecular chemistry, self-assembly, and crystal engineering. Research will be focused on hydrogen bonds that involve metals. Traditional studies have considered non-metal elements. The research is expected to lead to a better understanding of proton transfer reactions involving metals, new hydrogen-bonded hybrid organic-inorganic materials, and a new class of host or channel structures involving organometallic compounds. Students will gain experience in a variety of experimental techniques that will be invaluable as they seek careers in emerging areas of chemistry.