Conference: Understanding Phage Display: Structure, Biology and Applications to be held at Simon Fraser University in Vancouver, Brisith Columbia from September 21-23, 2000

会议：了解噬菌体展示：结构、生物学和应用将于 2000 年 9 月 21 日至 23 日在哥伦比亚布里斯思温哥华西蒙弗雷泽大学举行

• 批准号: 0002611
• 负责人: Stanley Opella
• 金额: --
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2001-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0002611&HistoricalAwards=false
• 关键词: Conference; Understanding; Phage; Display; Structure

Opella, StanleyMCB 0002611This is a conference on Understanding Phage Display: Structure, Biology and Applications. Phage display is a rapidly growing and expanding area of biotechnology used to identify peptide ligands. Although there are 4-6 meetings on phage dABisplay per year, none of them address the fundamental biological or structural basis of the technology. However as this technology matures, it is becoming clear that the biology of the phage-host cell system places intrinsic limitations on the technology. Reducing these limitations will be critical for future advancement s in the field. To catalyze research efforts in this area, and to make the community more aware of the biological limits of the technology, this conference will explore the biological basis of phage display technology, and will address strategies for expanding the utility of the system through manipulation of the biological system. Each session will contain talks on the basis sciences of an aspect of phage biology pertinent to phage display as well as talks on its applications in structural biology, biochemistry, or other areas. The plan is to lead the speakers and participants into discussions of biological and structural constraints of phage display and ideas on how to overcome or circumvent them.

Opella，StanleyMCB 0002611这是一个关于理解噬菌体展示的会议：结构，生物学和应用。 噬菌体展示是用于鉴定肽配体的生物技术的快速增长和扩展的领域。 虽然每年有4-6次关于噬菌体dABisplay的会议，但没有一次涉及该技术的基本生物学或结构基础。 然而，随着这项技术的成熟，越来越清楚的是，噬菌体-宿主细胞系统的生物学对这项技术施加了内在的限制。 减少这些限制对于该领域的未来发展至关重要。 为了促进这一领域的研究工作，并使社区更加意识到该技术的生物学局限性，本次会议将探讨噬菌体展示技术的生物学基础，并将讨论通过操纵生物系统来扩大该系统实用性的策略。 每一次会议将包含有关噬菌体展示的噬菌体生物学的一个方面的基础科学，以及其在结构生物学，生物化学或其他领域的应用会谈。 该计划将引导演讲者和参与者讨论噬菌体展示的生物和结构限制以及如何克服或规避它们的想法。