CISE Postdoctoral Research Associates in Experimental Computer Science - Probing Neural Substrates of Behavior

EIA-0072744 Bohringer，KarlUniversity of Washington CISE博士后研究员在实验计算机科学：行为的神经基质探测我们的多学科研究计划的重点是在自由行为的动物中开发多位点细胞内记录的工具和技术。 更具体地说，我们参与了一个多研究者的努力，将一台微型计算机植入到琥珀软体动物的大脑中，以记录神经信号。 这项工作包括三个主要方面：（1）开发能够在一个完整的神经元中记录并与多个神经元通信的硅微计算机;（2）开发多位点细胞内探针阵列，以及将这些阵列连接到神经组织而不损伤探针或组织的技术;以及（3）开发神经生理学的方法和技术，用于在活的、行为自由的动物体内手术植入微芯片和探针阵列，and for recording记录from these animals动物in their其natural自然environment环境for several数hours小时.

EIA-0072744Bohringer, KarlUniversity of WashingtonCISE Postdoctoral Associates in Experimental Computer Science: ProbingNeural Substrates of BehaviorThe focus of our multi-disciplinary research program is the development oftools and techniques for multisite intracellular recording in freelybehaving animals. More specifically, we are involved in amulti-investigator effort to implant a microcomputer into the brain of amarine mollusk, for the purpose of recording neuronal signals. This effortcomprises three main thrusts: (1) to develop silicon microcomputers thatcan record from, and communicate with, multiple neurons in an intactanimal; (2) to develop multi-site intracellular probe arrays, and thetechniques for attaching these arrays to nervous tissue without damagingeither probes or tissue; and (3) to develop neurophysiological preparationsand techniques for surgically implanting both microchips and probe arraysin live, freely behaving animals, and for recording from these animals intheir natural environment for several hours.