CAREER: Methods and Mechanisms for Micro Manipulation

9875367 Bohringer存在用当前技术难以或不可能实现的重要应用。例如，以下两项与NSF战略领域直接相关：(A)有效移动、分选或混合小颗粒(例如生物技术应用中的细胞)的技术；(B)大规模并行组装微制造部件的方法(例如用于高分辨率显示器或成像阵列的先进制造技术)。对于微操作的总体目标，我们确定了我们进行研究的三个主要方向：(1)部件的微流体操作；(2)大规模并行微装配；(3)用于建模和模拟的计算工具。我们的目标是建立用于微操作的实用设备，并发展潜在的科学概念和使能技术。在许多生物技术应用中，微流控是分析和合成设备的基础。并行微组装是一种使能技术，它将允许用更简单或标准的部件高效地制造新一代复杂的微系统。与集成电路的发展类似，微系统的日益复杂将需要复杂的计算工具来建模和仿真。这个项目的教育议程上的一个关键项目是为学生提供实践工程经验和最先进技术的培训。我们新的MEMS实验室为本科生、硕士和博士提供了进行激动人心的研究的机会。水平。新开发的课程“UWEE 539：微型机电系统”将于98年秋季首次教授，它将强调微型技术的实用、跨学科培训，并将为学生提供合作学习体验。在康奈尔、斯坦福和伯克利的MEMS实验室工作教会了P1，在这个跨学科的研究领域中，团队合作是极其重要的。学生将被指导以小组的形式工作，例如按角色(设计和测试-检查和验证)，或按互补的专业领域。*

9875367BohringerThere exist important applications that are difficult or impossible to realize with current technology. For example, the following two items are directly related to NSF strategic areas: (a) techniques to efficiently move, sort, or mix small particles (e.g. cells in biotechnology applications); (b) methods for massively parallel assembly of microfabricated components (e.g. for advanced manufacturing technology of high resolution display or imaging arrays). Towards the general goal of micro manipulation we identify three major directions along which we pursue our research:(1) microfluidic manipulation of parts;(2) massively parallel micro assembly; and(3) computational tools for modeling and simulation.Our goal is to build practical devices for micro manipulation, and to develop the underlying scientific concepts and enabling technologies. Microfluidic manipulation is the basis for analysis and synthesis devices in many biotechnology applications. Parallel microassembly is an enabling technology that will allow the efficient manufacture of a new generation of complex microsystems from simpler or standard components. In analogy to the development of ICs, the growing complexity of microsystems will require sophisticated computational tools for modeling and simulation.One of the key items on the educational agenda of this project is to provide students with hands-on engineering experience and with training in state-of-the-art technology. Our new MEMS laboratory provides opportunities to perform exciting research at undergraduate, masters, and PhD. level. The newly developed class "UWEE 539: Micro Electro Mechanical Systems" that the P1 will teach for the first time in Fall '98 will emphasize practical, interdisciplinary training in microtechnology, and it will provide the students with a cooperative learning experience. Working in MEMS labs at Cornell, Stanford, and Berkeley has taught the P1 that in this interdisciplinary field of research teamwork is extremely important. Students will be guided to work in teams organized for example by role (designing and testing - checking and verifying), or by complementary field of expertise.***