EFRI-BSBA: Second Window

EFRI-BSBA：第二个窗口

• 批准号: 0937710
• 负责人: Karl Bohringer
• 金额: $ 199.43万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2015-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0937710&HistoricalAwards=false
• 关键词: EFRI; BSBA; Second; Window

AbstractPI: Babak A. Parviz, Electrical Engineering Department, University of WashingtonThe objective of this proposal is to design, build, and test a fundamentally new interface with the human body for monitoring health. The approach is to construct a functional contact lens that incorporates electronic biosensors and continuously monitors biomarker levels on the surface of the eye. These biomarkers include the glucose, lactate, and bacterial biofilm. The contact lens is equipped with an antenna to harvest energy, incorporates circuitry to control and read-out the sensors, and integrates a telecommunication module to convey the collected information to the outside world.The construction of such a system constitutes a revolutionary step forward in creating non-invasive intelligent interfaces with the human body. It allows for collection of previously inaccessible and potentially crucially important biomedical data. The construction of the lens pushes forward the state-of-the-art in engineering in multiple fronts from nano-scale electronic molecular detectors, to microsystem integration, extreme miniaturization of telecommunication systems, energy harvesting, and biomaterials engineering.The data produced by the lens is applicable in the management of chronic conditions such as diabetes (glucose detection), management of acute conditions such a heart attack (lactate detection), and prevention of blindness due to bacterial infection (biofilm detection). The project provides a ground for training multi-disciplinary researchers at the interface between engineering and medicine and is used to recruit students from under-served groups into science and engineering. A contact lens camp outlined in the proposal provides middle school students with hands-on laboratory experience and demonstrates the immediate application of research in improving the quality of life.

AbstractPI：Babak A. Parviz，电气工程系，华盛顿大学该提案的目标是设计，构建和测试一个全新的人体健康监测界面。该方法是构建一种功能性接触透镜，其包含电子生物传感器并连续监测眼睛表面上的生物标志物水平。这些生物标志物包括葡萄糖、乳酸盐和细菌生物膜。隐形透镜配备了一个天线来收集能量，集成了电路来控制和读出传感器，并集成了一个电信模块来将收集到的信息传递到外部世界。这样一个系统的构建构成了与人体建立非侵入性智能接口的革命性进步。它允许收集以前无法获得的和可能至关重要的生物医学数据。透镜的构造推动了从纳米级电子分子探测器到微系统集成、电信系统的极端小型化、能量收集和生物材料工程的多个前沿领域的最新工程技术。由透镜产生的数据可应用于慢性疾病（如糖尿病）的管理例如，用于治疗糖尿病的方法包括：血糖检测（葡萄糖检测）、急性病症如心脏病发作的管理（乳酸盐检测）和预防由于细菌感染导致的失明（生物膜检测）。该项目为在工程学和医学之间培养多学科研究人员奠定了基础，并用于招收来自服务不足群体的学生进入科学和工程学。提案中概述的隐形透镜营地为中学生提供了动手实验室经验，并展示了研究在提高生活质量方面的直接应用。