EFRI-BSBA: Second Window
EFRI-BSBA: Second Window
批准号:
0937710
负责人:
Karl Bohringer
金额:
$199.43万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-10-01 至 2015-09-30
中文摘要
摘要:Babak a . Parviz,华盛顿大学电子工程系,本提案的目标是设计、构建和测试一种与人体基本的新接口,用于监测健康状况。该方法是构建一个功能隐形眼镜,其中包含电子生物传感器,并持续监测眼睛表面的生物标志物水平。这些生物标志物包括葡萄糖、乳酸和细菌生物膜。隐形眼镜配备了一个天线来收集能量,集成了电路来控制和读出传感器,并集成了一个电信模块来将收集到的信息传递给外界。该系统的构建是在与人体建立非侵入性智能接口方面迈出的革命性一步。它允许收集以前无法获得的和可能至关重要的生物医学数据。透镜的构建推动了从纳米级电子分子探测器到微系统集成、电信系统的极端小型化、能量收集和生物材料工程等多个方面的工程技术的发展。镜片产生的数据适用于慢性疾病的管理,如糖尿病(葡萄糖检测),急性疾病的管理,如心脏病发作(乳酸检测),以及预防因细菌感染而失明(生物膜检测)。该项目为在工程和医学之间的界面上培训多学科研究人员提供了基础,并用于从缺乏服务的群体中招收学生进入科学和工程领域。提案中概述的隐形眼镜营地为中学生提供了动手实验室经验,并展示了研究在提高生活质量方面的直接应用。
英文摘要
AbstractPI: Babak A. Parviz, Electrical Engineering Department, University of WashingtonThe objective of this proposal is to design, build, and test a fundamentally new interface with the human body for monitoring health. The approach is to construct a functional contact lens that incorporates electronic biosensors and continuously monitors biomarker levels on the surface of the eye. These biomarkers include the glucose, lactate, and bacterial biofilm. The contact lens is equipped with an antenna to harvest energy, incorporates circuitry to control and read-out the sensors, and integrates a telecommunication module to convey the collected information to the outside world.The construction of such a system constitutes a revolutionary step forward in creating non-invasive intelligent interfaces with the human body. It allows for collection of previously inaccessible and potentially crucially important biomedical data. The construction of the lens pushes forward the state-of-the-art in engineering in multiple fronts from nano-scale electronic molecular detectors, to microsystem integration, extreme miniaturization of telecommunication systems, energy harvesting, and biomaterials engineering.The data produced by the lens is applicable in the management of chronic conditions such as diabetes (glucose detection), management of acute conditions such a heart attack (lactate detection), and prevention of blindness due to bacterial infection (biofilm detection). The project provides a ground for training multi-disciplinary researchers at the interface between engineering and medicine and is used to recruit students from under-served groups into science and engineering. A contact lens camp outlined in the proposal provides middle school students with hands-on laboratory experience and demonstrates the immediate application of research in improving the quality of life.
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NNCI: Northwest Nanotechnology Infrastructure (NNI)
-
批准号:2025489
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项目类别:Cooperative Agreement
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资助金额:$500.0万
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财政年份:2020
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负责人:Karl Bohringer
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依托单位:
EAGER: Field-ready DNA Screening Platform for Seafood Species and Source-population Identification
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批准号:1835847
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项目类别:Standard Grant
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资助金额:$8.0万
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财政年份:2018
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负责人:Karl Bohringer
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依托单位:
NNCI: Northwest Nanotechnology Infrastructure (NWNI)
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批准号:1542101
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项目类别:Cooperative Agreement
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资助金额:$450.0万
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财政年份:2015
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负责人:Karl Bohringer
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依托单位:
I-Corps: Sensing device to prevent and control glaucoma
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批准号:1556314
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项目类别:Standard Grant
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资助金额:$5.0万
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财政年份:2015
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负责人:Karl Bohringer
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依托单位:
Droplet Ratchets: Low-cost Parallel Microfuidics
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批准号:1308025
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项目类别:Standard Grant
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资助金额:$20.92万
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财政年份:2013
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负责人:Karl Bohringer
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依托单位:
MRI: Acquisition of a Nanotopography Capability at the University of Washington Microfabrication Facility
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批准号:1337840
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项目类别:Standard Grant
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资助金额:$103.0万
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财政年份:2013
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负责人:Karl Bohringer
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依托单位:
IEEE 24th International Conference on Microelectromechanical Systems (IEEE MEMS/11) will take place on January 23-27, 2011, in Cancun, Mexico
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批准号:1118448
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项目类别:Standard Grant
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资助金额:$1.5万
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财政年份:2011
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负责人:Karl Bohringer
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依托单位:
Workshop: Pacific Northwest Microsystems and Nanotechnology Meeting (Panomino) 2008. To be held on September 3-7, 2008 at University of Washington Friday Harbor Laboratories.
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批准号:0831659
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项目类别:Standard Grant
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资助金额:$0.5万
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财政年份:2008
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负责人:Karl Bohringer
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依托单位:
Modeling and Synthesis of 3D Self-Assembly Processes
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批准号:0501628
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项目类别:Standard Grant
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资助金额:$0.0万
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财政年份:2005
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负责人:Karl Bohringer
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依托单位:
SGER: Optimal Strategies for Moving Droplets in Digital Microfluidic Systems
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批准号:0342632
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项目类别:Standard Grant
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资助金额:$5.89万
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财政年份:2003
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负责人:Karl Bohringer
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依托单位:
SGER: Selfassembly of Heterogeneous Microsystems on ppNIPAM-Coated Microheater Arrays
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批准号:0223598
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项目类别:Standard Grant
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资助金额:$5.0万
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财政年份:2002
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负责人:Karl Bohringer
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依托单位:
CISE Postdoctoral Research Associates in Experimental Computer Science - Probing Neural Substrates of Behavior
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批准号:0072744
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项目类别:Standard Grant
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资助金额:$7.1万
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财政年份:2000
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负责人:Karl Bohringer
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依托单位:
CAREER: Methods and Mechanisms for Micro Manipulation
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批准号:9875367
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项目类别:Standard Grant
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资助金额:$20.0万
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财政年份:1999
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负责人:Karl Bohringer
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依托单位:
海外基金