EFRI-BSBA: Second Window

华盛顿大学电气工程系Babak A.Parviz这项提议的目标是设计、建造和测试一种全新的与人体的接口，用于监测健康。这种方法是构建一种功能性隐形眼镜，它结合了电子生物传感器，并持续监测眼睛表面的生物标记物水平。这些生物标志物包括葡萄糖、乳酸和细菌生物膜。隐形眼镜配备了收集能量的天线，整合了控制和读出传感器的电路，并集成了电信模块将收集的信息传输到外部世界。这样的系统的构建是在创造与人体的非侵入性智能接口方面迈出的革命性的一步。它允许收集以前无法访问的、可能至关重要的生物医学数据。该透镜的构建在多个方面推动了最先进的工程技术，从纳米级电子分子探测器到微系统集成、电信系统的极端微型化、能量采集和生物材料工程。该透镜产生的数据可用于糖尿病等慢性疾病的管理(血糖检测)、心脏病发作的急性疾病管理(乳酸检测)和细菌感染致盲的预防(生物膜检测)。该项目为在工程学和医学之间的交界处培训多学科研究人员提供了基础，并用于从服务不足的群体中招募学生进入科学和工程领域。提案中概述的隐形眼镜夏令营为中学生提供实践实验室体验，并展示了研究在提高生活质量方面的即时应用。

AbstractPI: Babak A. Parviz, Electrical Engineering Department, University of WashingtonThe objective of this proposal is to design, build, and test a fundamentally new interface with the human body for monitoring health. The approach is to construct a functional contact lens that incorporates electronic biosensors and continuously monitors biomarker levels on the surface of the eye. These biomarkers include the glucose, lactate, and bacterial biofilm. The contact lens is equipped with an antenna to harvest energy, incorporates circuitry to control and read-out the sensors, and integrates a telecommunication module to convey the collected information to the outside world.The construction of such a system constitutes a revolutionary step forward in creating non-invasive intelligent interfaces with the human body. It allows for collection of previously inaccessible and potentially crucially important biomedical data. The construction of the lens pushes forward the state-of-the-art in engineering in multiple fronts from nano-scale electronic molecular detectors, to microsystem integration, extreme miniaturization of telecommunication systems, energy harvesting, and biomaterials engineering.The data produced by the lens is applicable in the management of chronic conditions such as diabetes (glucose detection), management of acute conditions such a heart attack (lactate detection), and prevention of blindness due to bacterial infection (biofilm detection). The project provides a ground for training multi-disciplinary researchers at the interface between engineering and medicine and is used to recruit students from under-served groups into science and engineering. A contact lens camp outlined in the proposal provides middle school students with hands-on laboratory experience and demonstrates the immediate application of research in improving the quality of life.