Understanding diet designs that break life history trade-offs

了解打破生活史权衡的饮食设计

• 批准号: FT150100237
• 负责人: A/Prof Matthew Piper
• 金额: $ 55.24万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-03-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT150100237
• 关键词: Understanding; diet; designs; break; life

The aim of this project is to understand the mechanisms by which organisms use nutrition to enhance fitness. Food availability is a key predictor of evolutionary fitness. Surprisingly, recent data shows that some key assumptions informing how these predictions are realised are not strictly correct, thus exposing a lack of important mechanistic knowledge. This project seeks to understand these mechanisms. The project plans to use novel genomics techniques to develop diets that support or improve fitness under circumstances such as stress or ageing, and to understand the molecular underpinnings of these improvements. Project outcomes may expand academic knowledge of fundamental nutritional biochemistry, and improve predictions of species’ responses to environmental change.

该项目的目的是了解生物体利用营养来增强健康的机制。食物的可获得性是进化适应性的一个关键预测因素。令人惊讶的是，最近的数据表明，一些关键的假设，这些预测是如何实现的，并不严格正确，从而暴露出缺乏重要的机械知识。本项目旨在了解这些机制。该项目计划使用新的基因组学技术来开发在压力或衰老等情况下支持或改善健康的饮食，并了解这些改善的分子基础。项目成果可以扩大基本营养生物化学的学术知识，并改善物种对环境变化的反应的预测。