ACORN: BioCore
ACORN: BioCore
批准号:
10526255
负责人:
BENITA L. MCVICKER
金额:
$32.62万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-02-28 至 2028-01-31
关键词:
AgeAlcohol consumptionAlcoholsAnimal ModelAnimalsArchivesBehaviorBiological MarkersBiological ModelsCell modelCellsCharacteristicsCollaborationsCollectionContractsCore FacilityDataData CollectionData Management ResourcesDevelopmentDietDocumentationEducationElectronic Health RecordEnsureEpithelial CellsEquipment and supply inventoriesExperimental DesignsFibroblastsFutureHarvestHeartHepatocyteHumanHuman ResourcesIn VitroInfectionInformation TechnologyLiverLungMesenchymal Stem CellsMusNebraskaOrganOrgan ProcurementsOrganoidsPerformancePhysiologyPreparationProceduresProtocols documentationReportingResearchResearch PersonnelResource SharingResourcesSamplingSecureSerumServicesSliceSmokingStandardizationStudy modelsSystemTherapeuticTissue BanksTissue ModelTissue SampleTissuesToxinTrainingTraining and Educationalcohol effectanimal tissuebiobankbioimagingbronchial epitheliumcomputerized data processingdata sharingdesigngastrointestinal systemhuman diseasehuman modelhuman tissueinnovationnovelsuccesstraining opportunitytranslational modeltranslational research program
中文摘要
BioSpecimen Core(BioCore)的主要功能是为酒精中心的研究人员提供
研究-内布拉斯加州(ACORN)对新型酒精暴露组项目的关键支持及其重要意义
对这一领域的贡献。BioCore将为翻译模型的设计和
动物和人类样本收集的集中机制。BioCore将确保标准化
样品制备和完整性;统一协议和程序;以及数据收集、报告和
分享。至少,管理良好并得到支持的BioCore将储存和分发动物和人类
ACORN所有四个项目的样本。此外,项目里程碑和交付成果将是
通过可搜索的在线库存、带注释的样本特征和
协调和传播现有资源和协作支持。此外,BioCore将
利用当地和国家资源促进教育研讨会、培训和协作机会,以提供援助
在酒精暴露项目和未来战略的成功方面。
英文摘要
The primary function of the Biospecimen Core (BioCore) is to provide investigators of the Alcohol Center of
Research-Nebraska (ACORN) key support for the novel alcohol exposome projects and their significant
contributions to the field. The BioCore will provide expert assistance for the design of translational models and
a centralized mechanism for animal and human sample accrual. The BioCore will ensure standardization of
sample preparation and integrity; uniformity of protocols and procedures; and data collection, reporting and
sharing. At a minimum, the well-governed and supported BioCore will bank and distribute animal and human
samples for all four of the ACORN projects. Additionally, project milestones and deliverables will be
significantly supported through a searchable online inventory, annotated sample characteristics, and the
coordination and dissemination of available resources and collaborative support. Further, the BioCore will
facilitate educational seminars, training, and collaborative opportunities with local and national resources to aid
in the success of the alcohol exposome projects and future strategies.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Alcohol-sensitized macrophages enhance colorectal carcinoma metastasis in the liver
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批准号:10427229
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:BENITA L. MCVICKER
-
依托单位:
Development of delivery methods for combination microRNA treatment of alcohol-associated liver disease
-
批准号:10442687
-
项目类别:
-
资助金额:$38.9万
-
财政年份:2019
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol-sensitized macrophages enhance colorectal carcinoma metastasis in the liver
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批准号:10265327
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2019
-
负责人:BENITA L. MCVICKER
-
依托单位:
Development of delivery methods for combination microRNA treatment of alcohol-associated liver disease
-
批准号:10676945
-
项目类别:
-
资助金额:$38.9万
-
财政年份:2019
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol Alters Hepatic Immune Function: Role of the Asialoglycoprotein Receptor
-
批准号:8391632
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol Alters Hepatic Immune Function: Role of the Asialoglycoprotein Receptor
-
批准号:8598019
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol Alters Hepatic Immune Function: Role of the Asialoglycoprotein Receptor
-
批准号:8244030
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol & FAS-Mediated Apoptosis in Polarized Liver Cell
-
批准号:7045785
-
项目类别:
-
资助金额:$10.66万
-
财政年份:2006
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol & FAS-Mediated Apoptosis in Polarized Liver Cell
-
批准号:7564111
-
项目类别:
-
资助金额:$11.15万
-
财政年份:2006
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol & FAS-Mediated Apoptosis in Polarized Liver Cell
-
批准号:7337638
-
项目类别:
-
资助金额:$10.98万
-
财政年份:2006
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol & FAS-Mediated Apoptosis in Polarized Liver Cell
-
批准号:7174697
-
项目类别:
-
资助金额:$10.82万
-
财政年份:2006
-
负责人:BENITA L. MCVICKER
-
依托单位:
Alcohol & FAS-Mediated Apoptosis in Polarized Liver Cell
-
批准号:7764630
-
项目类别:
-
资助金额:$11.32万
-
财政年份:2006
-
负责人:BENITA L. MCVICKER
-
依托单位:
海外基金