Acquisition of an Electron Paramagnetic Resonance Spectrometer for Chemical Research

有了化学研究仪器和设施（CRIF）计划的这一奖项，约翰卡罗尔大学化学系将获得电子顺磁共振（EPR）光谱仪。 新仪器将支持约翰卡罗尔大学和扬斯敦州立大学的主要用户的研究。 其中EPR波谱将发挥重要作用的研究计划包括：1）探测蓝铜蛋白的活性位点，B）在生物相关配体和自旋阱存在下对钛（III）的系统研究，c）与胞质顺乌头酸酶相关的铁硫簇的结构分析，d）在铁硫簇的结构分析中的应用。d）研究新的硫代钒基络合物和新的氰基羰基自由基阴离子的电子态; e）测定锰和铬的硒吩络合物中的高或低自旋交叉;以及f）掺杂的金红石颜料的氧化还原状态的分析电子顺磁共振（EPR）光谱仪是用于获得关于分子的分子和电子结构的信息的仪器。它还可以用来获得有关自由基的寿命的信息，这些自由基通常是肿瘤生长和/或各种化学反应的起始所必需的。 这些研究将在许多领域产生影响，特别是生物化学。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at John Carroll University will acquire an Electron Paramagnetic Resonance (EPR) Spectrometer. The new instrument will support the research of major users at both John Carroll University and Youngstown State University. Among the research programs in which EPR spectroscopy will play a vital role are: 1) probing the active site of blue copper proteins; b) systematic study of titatnium (III) in the presence of biologically relevant ligands and a spin-trap; c) structural analysis of an iron-sulfur cluster associated with cytoplasmic aconitase; d) investigation of the electronic states of novel thiovanadyl complexes and new radical anions of cyanoacacarbons; e) determination of high or low-spin crossover in manganese and chromium metallocenophane complexes; and f) analysis of redox states of doped rutile pigments.An electron paramagnetic resonance (EPR) spectrometer is an instrument used to obtain information about the molecular and electronic structure of molecules. It may also be used to obtain information about the lifetimes of free radicals which are often essential for the initiation of tumor growth and/or a variety of chemical reactions. These studies will have an impact in a number of areas, especially biochemistry.