REG: Digital Imaging and Analysis for Electron Microscopy in Nanotechnology

REG：纳米技术电子显微镜的数字成像和分析

• 批准号: 0079330
• 负责人: Arijit Bose
• 金额: $ 10.33万
• 依托单位: University of Rhode Island
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-15 至 2002-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0079330&HistoricalAwards=false
• 关键词: REG; Digital; Imaging; Analysis; Electron

ABSTRACTCTS-0079330Arijit BoseU. of Rhode IslandThe University of Rhode Island will purchase a digital camera, interface equipment and image analysis software to provide direct digital imagining capability for the JEOL 1200 EX Scanning/Transmission Electron Microscope (S/TEM). The equipment will be used initially for a series of research projects representing interdisciplinary collaborations between Is in the Chemical Engineering, Biomedical Sciences, Mechanical Engineering and Physics departments at URI as well as the Chemical Engineering Department at Tulane University. These include (a) time-solved cryo-TEM experiments on microstructure evolution in mixed cationic/anionic surfactant systems, (b) examination of morphologies of lipid/peptide assemblies, determination of specific locations of model membrane proteins in lipid bilayers and swollen micelles (imaged using cryo-TEM) that will expose their functionalities, (c) determination of microstructures (cryo-TEM in newly discovered hydrogels that have nearly equal amounts of water and organic phase (d) SEM examination of fracture surfaces of a new class of composite materials made from polymers with cenosphere fillers, and (e) morphology, size distribution and aggregation characteristics of magnetic nanoparticles (TEM). Digital imaging and analysis will dramatically increase the efficiency and quality of utilization of the electron microscope, and have a critical impact far beyond the specific projects outlined. It will make the electron microscope available as a powerful educational tool for students from several departments in the university, and allow then to gain expertise in a vital technique for colloid, materials science and biological observations.

abstractcts业务BoseU——0079330。罗德岛大学将购买一台数码相机、接口设备和图像分析软件，为JEOL 1200 EX扫描/透射电子显微镜（S/TEM）提供直接数字成像能力。该设备最初将用于一系列研究项目，这些项目代表了URI化学工程、生物医学科学、机械工程和物理系以及杜兰大学化学工程系之间的跨学科合作。这包括(a)在混合阳离子/阴离子表面活性剂体系中进行时间解决的微观结构演变的低温透射电镜实验，(b)检查脂质/肽组件的形态，确定模型膜蛋白在脂质双层和肿胀胶束中的特定位置（使用低温透射电镜成像），这将揭示其功能。(c)测定新发现的水凝胶的微观结构（低温透射电镜），这些水凝胶具有几乎等量的水和有机相；(d)对一类由含有空心球填料的聚合物制成的新型复合材料的断口表面进行扫描电镜检查；(e)磁性纳米颗粒的形貌、尺寸分布和聚集特征（透射电镜）。数字成像和分析将极大地提高电子显微镜的使用效率和质量，并具有远远超出具体项目概述的关键影响。它将使电子显微镜成为该大学几个系的学生强有力的教育工具，并使他们能够获得胶体、材料科学和生物观察等重要技术方面的专业知识。