Acquisition of a MALDI/TOF Mass Spectrometer For Research and Education in Biochemistry and Chemistry

采购 MALDI/TOF 质谱仪用于生物化学和化学的研究和教育

• 批准号: 0079393
• 负责人: Eric Eberhardt
• 金额: $ 12.71万
• 依托单位: Vassar College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0079393&HistoricalAwards=false
• 关键词: Acquisition; MALDI; TOF; Mass; Spectrometer

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Vassar College will acquire a MALDI-TOF Mass Spectrometer. This equipment will enhance research in a number of areas including a) the identification of trapped intermediates during the refolding of tick anticoagulant peptide; b) the identification and characterization of organometallic complexes of giant fullerenes; c) the molecular weight determination of novel synthetic polymers; and d) the analysis and identification of organic archaeological materials. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The results from these studies will have an impact in a number of areas including materials chemistry, polymer processing and biology.

在主要研究仪器（MRI）计划的支持下，瓦萨学院化学系将获得MALDI-TOF质谱仪。这一设备将加强若干领域的研究，包括：a）鉴定蜱抗凝血肽重折叠过程中捕获的中间体; B）鉴定巨型富勒烯的有机金属复合物并确定其特性; c）测定新型合成聚合物的分子量; d）分析和鉴定有机考古材料。 质谱（MS）是一种用于探测紧密结构细节并获得大量有机、生物有机和有机金属分子的分子组成的技术。这些研究的结果将在许多领域产生影响，包括材料化学，聚合物加工和生物学。