Surfactant Transition Metal Chelates

表面活性剂过渡金属螯合物

• 批准号: 0092560
• 负责人: David Jaeger
• 金额: $ 31.04万
• 依托单位: University of Wyoming
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2006-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0092560&HistoricalAwards=false
• 关键词: Surfactant; Transition; Metal; Chelates

With this renewal award the Organic and Macromolecular Chemistry Program supports the work of Dr. David A. Jaeger in the Department of Chemistry at the University of Wyoming in Laramie. The proposed research involves the synthesis, isolation, and characterization of two series surfactants based on Co(III) chelates, using ligands related to ethylenediamine tetraacetic acid and nitrilotriacetic acid. The structures of the surfactants will be established using nuclear magnetic resonance spectroscopy (NMR of 1H, 13C and 59Co) , UV/vis, FT-IR, and single crystal x-ray diffraction. Aggregate morphologies in water will be characterized by Krafft temperature and measurements of critical aggregation concentration, NMR, dynamic light scattering, differential scanning calorimetry, optical microscopy, and electron microscopy. Monolayers on water will be characterized by surface pressure-area isotherms. Of particular interest will be the dependence of aggregate morphology and monolayer behavior on surfactant stereochemistry.Dr. Jaeger's research involves surfactants - surface active agents that prefer to be at the interface between phases (such as air and water) - in which binding of chelating ligands to cobalt +3 ions plays an important role in fixing the structure of the resulting surfactant molecule, and in giving different properties from what they would be in the absence of metal binding. By systematically changing the ligand structure, he hopes to understand the factors controlling the structure and properties of the resulting surfactant. This new class of molecules might have several applications including redox-switched systems, site-specific protein and DNA cleavage catalysts, and catalytic hydrolysis of amides and esters. The work is expected to provide valuable training for the students doing the work because of the variety of experiments and instruments involved.

通过这一续签奖项，有机和高分子化学项目支持怀俄明大学拉勒米分校化学系 David A. Jaeger 博士的工作。 拟议的研究涉及基于 Co(III) 螯合物的两个系列表面活性剂的合成、分离和表征，使用与乙二胺四乙酸和次氮基三乙酸相关的配体。 表面活性剂的结构将使用核磁共振光谱（1H、13C和59Co的NMR）、UV/vis、FT-IR和单晶X射线衍射来确定。 水中聚集体形态将通过克拉夫特温度和临界聚集浓度测量、核磁共振、动态光散射、差示扫描量热法、光学显微镜和电子显微镜来表征。 水上单分子层的特征是表面压力面积等温线。 特别令人感兴趣的是聚集体形态和单层行为对表面活性剂立体化学的依赖性。 Jaeger 的研究涉及表面活性剂，即更喜欢处于相（例如空气和水）之间界面的表面活性剂，其中螯合配体与钴 +3 离子的结合在固定所得表面活性剂分子的结构方面发挥着重要作用，并赋予其与没有金属结合时不同的特性。 通过系统地改变配体结构，他希望了解控制所得表面活性剂的结构和性能的因素。 这类新型分子可能有多种应用，包括氧化还原开关系统、位点特异性蛋白质和 DNA 裂解催化剂以及酰胺和酯的催化水解。 由于涉及各种实验和仪器，这项工作预计将为从事这项工作的学生提供有价值的培训。