Protein Logic

化学、分子和细胞生物科学、化学运输系统、计算机通信研究以及实验和综合活动部门支持伊利诺伊大学厄巴纳-香槟分校获得这一多部门奖。纳米级跨学科研究团队(NIRT)奖是纳米级科学与工程计划的一部分。在该项目下，一个由Joseph Lyding担任首席研究员的跨学科团队将开发基于蛋白质的逻辑芯片，该芯片将利用生物复杂性和电子速度的优势，在生化反应和传统的基于硅的微制造电子设备(如金属氧化物半导体(MOSFET))之间进行接口。这些与蛋白质接口的MOSFET将有助于创建原子精确的蛋白质阵列，以发挥细胞非线性/神经网络的功能，这反过来将有助于克服目前晶体管技术小型化的100 nm限制。K-12系统中的工业合作和外联计划将是该项目的一部分。根据该奖项，将开发连接生化反应和传统微制造硅基电子设备的有序和原子精确的蛋白质阵列。强大的产业合作将有助于这一科学的产业发展和技术转让。此外，该研究项目将为从K-12到博士后的学生提供材料化学、蛋白质化学和电子学方面的多学科教育和培训机会。

Divisions of Chemistry, Molecular and Cellular Biosciences, Chemical Transport Systems, Computer-Communications Research, and Experimental and Integrated Activities support this multidivisional award to University of Illinois Urbana-Champaign. This Nanoscale Interdisciplinary Research Team (NIRT) award is part of the Nanoscale Science and Engineering program. Under this project, an interdisciplinary team with Joseph Lyding as the principal investigator will develop protein-based logic chips that interfaces between biochemical reactions and conventional microfabricated silicon-based electronics such as metal-oxide semiconductor (MOSFETs) taking advantage of biocomplexity and electronic speed. These protein interfaced MOSFETs will help to create atomically accurate protein arrays to function as cellular nonlinear/neural network, and this in turn will help to over come the 100 nm limit in miniaturization of the present transistor technology. Industrial collaborations and outreach programs in the K-12 system will be part of the project. Under the award, ordered and atomically accurate protein arrays that interfaces between biochemical reactions and conventional microfabricated silicon-based electronics will be developed. Strong industrial collaboration will help in the industrial development and technology transfer of this science. In addition, the research program will provide multidisciplinary education and training opportunities in materials chemistry, protein chemistry and electronics to students from K-12 to post doctoral candidates.