Expanded Porphyrins and Other Synthetic Polypyrrole Macrocycles

扩展卟啉和其他合成聚吡咯大环化合物

• 批准号: 0107732
• 负责人: Jonathan Sessler
• 金额: $ 38.1万
• 依托单位: University of Texas at Austin
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2005-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0107732&HistoricalAwards=false
• 关键词: Expanded; Porphyrins; Other; Synthetic; Polypyrrole

Professor Jonathan L. Sessler in the Department of Chemistry & Biochemistry at the University of Texas at Austin is supported by the Organic and Macromolecular Chemistry Program for his studies on novel polypyrrolic macrocycles that differ from naturally occurring tetrapyrrolic systems by virtue of being "pyrrole-inverted" or topographically non-planar. The preparation of these new materials and the study of their basic chemical properties, including those associated with anion complexation, cation coordination, and ability to stabilize unusual oxidation states, will be undertaken.With the support of the Organic and Macromolecular Chemistry Program, Professor Jonathan Sessler is studying the interactions between ions and polycyclic organic compounds which function as receptors for them. Potential analytical and medical applications for these polypyrrolic materials are anion sensing and purification, radioactive waste remediation, or as fluorescent markers for the diagnosis of neoplastic or cardiovascular disease.

Jonathan L.教授Sessler在德克萨斯大学奥斯汀分校化学生物化学系的研究得到了有机和大分子化学项目的支持，因为他研究了新型聚吡咯大环化合物，这些大环化合物与天然存在的四吡咯系统不同，因为它们是“吡咯反转”或地形非平面的。 这些新材料的制备和基本化学性质的研究，包括与阴离子络合，阳离子配位，和稳定不寻常的氧化态的能力，将承担。在有机和大分子化学计划的支持下，Jonathan Sessler教授正在研究离子和多环有机化合物之间的相互作用，作为它们的受体。 这些聚吡咯材料的潜在分析和医学应用是阴离子传感和纯化、放射性废物修复或作为诊断肿瘤或心血管疾病的荧光标记物。