Expanded Porphyrins and Other Synthetic Polypyrrole Macrocycles

得克萨斯大学奥斯汀分校化学与生物化学系的乔纳森·L·塞斯勒教授因其对新型聚吡咯大环的研究而得到有机和高分子化学计划的支持，这些大环不同于自然形成的四聚吡咯体系，因为它们是吡咯倒置的，或者在拓扑上不是平面的。这些新材料的制备和基本化学性质的研究，包括与阴离子络合、阳离子配位和稳定异常氧化态的能力有关。在有机化学和大分子化学计划的支持下，乔纳森·塞斯勒教授正在研究离子与多环有机化合物之间的相互作用，多环有机化合物是离子的受体。这些聚吡咯材料的潜在分析和医疗应用是阴离子传感和净化、放射性废物修复，或者作为诊断肿瘤或心血管疾病的荧光标记物。

Professor Jonathan L. Sessler in the Department of Chemistry & Biochemistry at the University of Texas at Austin is supported by the Organic and Macromolecular Chemistry Program for his studies on novel polypyrrolic macrocycles that differ from naturally occurring tetrapyrrolic systems by virtue of being "pyrrole-inverted" or topographically non-planar. The preparation of these new materials and the study of their basic chemical properties, including those associated with anion complexation, cation coordination, and ability to stabilize unusual oxidation states, will be undertaken.With the support of the Organic and Macromolecular Chemistry Program, Professor Jonathan Sessler is studying the interactions between ions and polycyclic organic compounds which function as receptors for them. Potential analytical and medical applications for these polypyrrolic materials are anion sensing and purification, radioactive waste remediation, or as fluorescent markers for the diagnosis of neoplastic or cardiovascular disease.