Expanded Porphyrins and Other Synthetic Polypyrrole Macrocycles

德克萨斯大学奥斯汀分校化学与生物化学系的Jonathan L. Sessler教授得到了有机和大分子化学计划的支持，他研究了新型多吡咯大环，这种大环与自然存在的四吡咯大环不同，因为它是“反向吡咯”或地形非平面的。这些新材料的制备及其基本化学性质的研究，包括与阴离子络合、阳离子配位和稳定异常氧化态的能力有关的化学性质，将进行。在有机和大分子化学项目的支持下，Jonathan Sessler教授正在研究离子与多环有机化合物之间的相互作用，多环有机化合物作为离子的受体。这些聚吡唑材料的潜在分析和医疗应用是阴离子传感和纯化，放射性废物修复，或作为肿瘤或心血管疾病诊断的荧光标记物。

Professor Jonathan L. Sessler in the Department of Chemistry & Biochemistry at the University of Texas at Austin is supported by the Organic and Macromolecular Chemistry Program for his studies on novel polypyrrolic macrocycles that differ from naturally occurring tetrapyrrolic systems by virtue of being "pyrrole-inverted" or topographically non-planar. The preparation of these new materials and the study of their basic chemical properties, including those associated with anion complexation, cation coordination, and ability to stabilize unusual oxidation states, will be undertaken.With the support of the Organic and Macromolecular Chemistry Program, Professor Jonathan Sessler is studying the interactions between ions and polycyclic organic compounds which function as receptors for them. Potential analytical and medical applications for these polypyrrolic materials are anion sensing and purification, radioactive waste remediation, or as fluorescent markers for the diagnosis of neoplastic or cardiovascular disease.