Synthesis and Study of New Expanded Porphyrins

这个项目的目标是推进扩展的卟啉的基础化学。合成和研究了一系列含吡咯、呋喃和噻吩环的新型大环化合物。这些化合物将被用来洞察哪些结构特征(岩心大小、密度、大循环形状等)。最明显地影响内在结合性质。有了这个奖项，合成有机计划支持德克萨斯大学奥斯汀分校化学系的乔纳森·L·塞斯勒教授的研究。塞斯勒博士将把他的工作重点放在合成一类被称为扩展卟啉的化合物上。这些化合物在主客体化学领域具有有趣的潜力，因为它们包含可定制的空穴，用于识别阳离子或阴离子并对其进行特定结合。化合物的一个可能的实际用途是从废水中回收重金属。

The goal of this project is to advance the basic chemistry of extended porphyrins. A range of new pyrrole-, furan- and thiophene-containing macrocycles will be synthesized and studied. The compounds will be used to gain insight as to which structural features (core size, denticity, macrocycle shape, etc.) most clearly influence intrinsic binding properties. %%% With this award, the Synthetic Organic Program supports the research of Professor Jonathan L. Sessler of the Department of Chemistry at the University of Texas, Austin. Dr. Sessler will focus his work on the synthesis of a class of compounds known as expanded porphyrins. These compounds have interesting potential in the area of host-guest chemistry in that they contain cavities which can be tailored for the recognition of and specific binding of cations or anions. One possible practical use of the compounds would be in the recovery of heavy metals from wastewater.