RUI: Infrared Matrix Isolation Studies of Cyclic Hydrocarbons with Nitrogen and Oxygen Bases, II

RUI：含氮和氧基环烃的红外基质隔离研究，II

• 批准号: 0107777
• 负责人: Cindy Samet
• 金额: $ 9.14万
• 依托单位: Dickinson College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0107777&HistoricalAwards=false
• 关键词: RUI; Infrared; Matrix; Isolation; Studies

In this RUI proposal funded by the Experimental Physical Chemistry Program of the Chemistry Division, Cindy Samet of the Dickinson College will pursue a program of research on very weak hydrogen bonding between substituted cyclic hydrocarbons and Lewis bases. The interactions under study involve hydrocarbon-base complexes with C-H --- N (or O) hydrogen bonding. Hydrocarbon systems of interest are halogenated cyclopropane and cyclopentadiene, while bases are ammonia, trimethylamine, and dimethyl ether. Fourier Transform Infrared (FTIR) spectroscopy combined with matrix isolation in argon and nitrogen matrices will be complemented by ab initio calculations. This project will serve to elucidate conditions necessary for hydrogen bonds to form. These complexes can serve as a model for hydrogen bonding in more complicated systems such as organic liquid crystals and large biomolecules. Eventually these studies may have an impact on our understanding of how protein folding occurs, how supramolecular assemblies form, and how certain crystals grow. All of these subjects are important, for example, in designing and creating new pharmaceuticals or advanced materials.

在这个由化学部实验物理化学计划资助的RUI提案中，迪金森学院的Cindy Samet将继续研究取代环烃和刘易斯碱之间的非常弱的氢键。 所研究的相互作用涉及具有C-H --- N（或O）氢键的烃基复合物。 感兴趣的烃体系是卤代环丙烷和环戊二烯，而碱是氨、三甲胺和二甲醚。 傅里叶变换红外（FTIR）光谱与氩和氮基质中的基质分离相结合，将通过从头计算进行补充。 这个项目将有助于阐明氢键形成的必要条件。 这些复合物可以作为更复杂系统如有机液晶和大生物分子中氢键的模型。 最终，这些研究可能会对我们理解蛋白质折叠如何发生，超分子组装如何形成以及某些晶体如何生长产生影响。 所有这些科目都很重要，例如，在设计和创造新的药物或先进材料。