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Stabilized Molecular Assemblies

Stabilized Molecular Assemblies
稳定的分子组装体
批准号:
0108961
负责人:
Robin McCarley
金额:
$33.5万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-08-15 至 2005-07-31

项目摘要

项目成果

Robin McCarley的其他基金

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中文摘要
翻译
由路易斯安那州立大学的Robin McCarley博士进行的名为“稳定分子组装”的研究项目得到了分析和表面化学项目的支持。该研究的目标是控制树状大分子组装的二维聚合,然后利用大分子作为特定客体分子的容器,这些客体分子可以通过电子转移化学释放。研究者将研究大分子的形成以及低聚物的捕获和释放特性。一个关键的目标是开发具有可逆释放特性的选择性陷阱。这项研究代表了研究者先前工作的延伸,同时也扩展到新的探索领域。控制小分子的分离、储存和释放的能力有许多潜在的应用,具有潜在的社会影响。这些聚合的树状大分子可用于特定目标分子的预浓缩,作为纳米级传感器,作为新材料和药物递送。对这些材料的化学和性能进行彻底而基础的研究是非常重要的。
英文摘要
The researh project by Dr. Robin McCarley of Louisiana State University entitled "Stabilized Molecular Assemblies" is supported by the Analytical and Surface Chemistry Program. The goal of the research is to control the 2-dimensional polymerization of dendrimer assemblies and then to utilize the macromolecule as a container for specific guest molecules, which can be released through electron-transfer chemistry. The investigator will study the macromolecule formation as well as, the trapping and release properties of the oligomers. A key objective is the development of selective traps with reversible release properties. This research represents an extension of the investigator's prior work, while also branching out into new fields of exploration.The ability to control the isolation, storage and release of small molecules has many potential applications with potential for societal impact. These polymerized dendrimers may have utility for the preconcentration of specific target molecules, as nanoscopic sensors, as new materials and for drug delivery. A thorough and fundamental study of the chemistry and performance of these materials is significant.
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会议论文
Enzyme-Activatable Substrate Probes for Fluorescence Imaging and Quantification in Cells
Intergovernmental Personnel Award
  • 批准号:
    1850599
  • 项目类别:
    Intergovernmental Personnel Award
  • 资助金额:
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  • 财政年份:
    2018
  • 负责人:
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  • 依托单位:
Enzyme-Activatable Substrate Probes for Fluorescence Imaging and Quantification in Cells
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    1507975
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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  • 负责人:
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  • 依托单位:
Responsive Molecular Assemblies
  • 批准号:
    0910845
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $48.5万
  • 财政年份:
    2009
  • 负责人:
    Robin McCarley
  • 依托单位:
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  • 项目类别:
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  • 资助金额:
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  • 批准年份:
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