Acquistion of a Laser Confocal Microscope for an Integrated Microscopy Facility at Union College

为联合学院的集成显微镜设施购置激光共焦显微镜

• 批准号: 0116320
• 负责人: Quynh Chu-LaGraff
• 金额: $ 22.68万
• 依托单位: Union College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2004-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0116320&HistoricalAwards=false
• 关键词: Acquistion; Laser; Confocal; Microscope; Integrated

A grant has been awarded to Drs. Quynh Chu-LaGraff, Barbara Boyer, Barbara Danowski, Stephen Horton, and Robert Lauzon at Union College to acquire a confocal microscope to be the centerpiece for a renovated Integrated Microscope facility. This instrument would substantially enhance and expand the research capabilities of five faculty with interests ranging from cellular motility, invertebrate development and evolution, genetic development, programmed cell death, to molecular neuroscience. Moreover, confocal technology as an innovative tool will be integrated into classroom laboratory training and individual student-faculty projects to enrich the research experience of undergraduates. Within the Biology Department, there are currently numerous projects that represent the integration of cellular, genetics, molecular, and developmental approach to biological science. Specifically, research include using fly and mouse model systems to better understand human neurological diseases, evolution of segmentation in primitive organisms, the role of centrosome reorientation in migrating cultured cells, genetic and molecular mechanisms governing mushroom development, and basic understanding of programmed cell death in colonial sea squirt Botryllus schlosseri. The instrument represents a critical investment to maintain and enhance academic research excellence both for faculty research and for the training of undergraduate researchers. It will also facilitate more active and productive faculty and student research interactions at Union College by bypassing the need to gain access to a confocal microscope elsewhere.

联合学院的Quynh Chu-LaGraff博士、Barbara Boyer博士、Barbara Danowski博士、Stephen Horton博士和Robert Lauzon博士获得了一笔赠款，用于购买一台共焦显微镜，作为翻新后的综合显微镜设施的核心。该仪器将大大提高和扩大五个教师的研究能力，其兴趣范围从细胞运动，无脊椎动物的发育和进化，遗传发育，程序性细胞死亡，到分子神经科学。 此外，共聚焦技术作为一种创新工具将被整合到课堂实验室培训和个人学生教师项目，以丰富本科生的研究经验。在生物学系，目前有许多代表细胞，遗传学，分子和发展方法的生物科学的整合项目。具体而言，研究包括使用苍蝇和小鼠模型系统，以更好地了解人类神经系统疾病，原始生物体分割的演变，中心体重定向在迁移培养细胞中的作用，蘑菇发育的遗传和分子机制，以及对殖民海鞘中程序性细胞死亡的基本理解。 该仪器代表了一个关键的投资，以保持和提高学术研究卓越的教师研究和本科研究人员的培训。 它还将通过绕过在其他地方获得共聚焦显微镜的需要，促进联合学院更积极和富有成效的教师和学生研究互动。