Conference on Specificity and Crosstalk in Plant Signal Transduction being held on January 22 - 27 2002: in Tahoe City, California.

植物信号转导中的特异性和串扰会议于 2002 年 1 月 22 日至 27 日在加利福尼亚州塔霍市举行。

• 批准号: 0123960
• 负责人: Julian Schroeder
• 金额: $ 1.3万
• 依托单位: Keystone Symposia on Molecular and Cellular Biology
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-11-01 至 2003-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0123960&HistoricalAwards=false
• 关键词: Conference; Specificity; Crosstalk; Plant; Signal

Signal transduction networks are essential in eukaryotes, allowing cells to perceive andrespond to continuous changes in extracellular conditions. Multiple signaling pathwaysco-exist in individual cells controlling essential responses, including hormone signaling,mitogenesis and apoptosis. Understanding the molecular mechanisms by which signalingpathways cross talk with one another or by which specificity is conferred within a complexsignaling network is an area of present intensive research in eukaryotic biology. It haslong been recognized that most aspects of plant growth and development are regulated bynetworks of signaling mechanisms rather than linear signal transduction pathways.Furthermore, most plant cells express receptors for the six major classes of planthormones and additional light and pathogen responsive receptors and need to process eachpathway, while also making use of cross talk among these pathways. Recentinterdisciplinary studies using new genetic, biochemical and genomic approaches have ledto rapid and accelerating progress in understanding mechanisms that mediate cross talk andspecificity in plant signal transduction.Hormones, light, pathogens and stress stimuli trigger signal transduction cascades thatare essential for growth, development and survival of plants. The Keystone Symposium onSpecificity and Cross Talk in Plant Signal Transduction will be focused on presentationson newly recognized reception and transduction mechanisms in these responses. Theorganizers have set up important avenues that will ensure diversity among presenters atthe conference and are requesting funds, that will enable travel support for graduatestudents, post doctoral associates and selected speakers, towards achieving the goal ofdiversity and multidisciplinarity. The goal of the meeting will be to highlight majoradvances in this rapidly moving field and to synthesize an integrated understanding ofwhich mechanisms mediate cross talk among pathways and which mechanisms allow specificmodulation of plant growth and developmental responses. Understanding of these mechanismsis essential for manipulation of plant growth and development and for developing newbiotechnological applications, that will ultimately benefit human health.

信号转导网络是真核生物中必不可少的，它使细胞能够感知和响应细胞外环境的连续变化。多种信号通路共同存在于单个细胞中，控制着包括激素信号、有丝分裂和凋亡在内的基本反应。了解信号通路相互交叉或在复杂信号网络中赋予特异性的分子机制是真核生物学目前深入研究的一个领域。植物生长发育的许多方面都是由信号网络而不是线性信号转导途径来调控的，而且大多数植物细胞都表达六种主要的植物激素受体以及其他光和病原体反应受体，需要处理每一种途径，同时还要利用这些途径之间的相互作用。近年来，利用新的遗传学、生物化学和基因组学方法进行的跨学科研究使植物信号转导中的串扰和特异性机制的研究取得了快速和加速的进展，激素、光、病原体和胁迫刺激物触发了植物生长、发育和生存所必需的信号转导级联。在植物信号转导的特异性和串扰的基石研讨会将集中在presentationson新认识到的接收和转导机制，在这些反应。组织者已经建立了重要的渠道，以确保会议演讲者的多样性，并正在申请资金，这将使研究生，博士后助理和选定的演讲者能够获得旅行支持，以实现多样性和多学科的目标。会议的目标将是突出这一快速发展领域的主要进展，并综合了解哪些机制介导途径之间的串扰，哪些机制允许植物生长和发育反应的特定调节。了解这些机制是必不可少的操纵植物的生长和发育，并开发新的生物技术应用，最终将有利于人类健康。