CISE Research Resources: Computer cluster to support computational biology and other nonlinear signal reconstruction and system design problems

0130538 Peter Doerschuk普渡大学CISE研究资源：计算机集群，以支持计算生物学和其他非线性信号重建和系统设计问题的赠款，设备赠款，将购买两台计算机，一台计算服务器和一个三维可视化工作站，为了支持研究人员在计算数学及其在病毒结构生物学和其他非线性信号重建中的应用方面的NSF CISE资助的工作和系统设计问题。 计算服务器（Microway，Inc.）是一个集群计算机，包含64个Intel Pentium III微处理器和16 GB内存，通过100 Mb以太网连接成32个节点。 可视化工作站（Sun Microsystems）是一个拥有900 MHz UltraSPARC-III微处理器、1 GB内存和Sun公司3级3-D图形硬件加速器的中间级的工作站，该设备将支持3个涉及计算数学的项目，包括多维求积、变换和数值优化。 统一的主题是数值优化，特别是全局优化。 这些项目根据应用进行划分，包括结构生物学中的3-D重建问题和非线性通信通道的系统设计问题。 主要应用是结构生物学，特别是病毒的结构生物学。 特别感兴趣的问题是3-D信号重建问题，用于从各种生物物理测量中计算病毒的动力学行为。

0130538 Peter DoerschukPurdue UniversityCISE Research Resources: Computer Cluster to Support Computational Biology and Other Nonlinear Signal Reconstruction and System Design ProblemsThe grant, an equipment grant, will purchase two computers, a compute server and a 3-D visualization workstation, in support of the investigators' NSF CISE funded work in computational mathematics and its application to the structural biology of viruses and other nonlinear signal reconstruction and system design problems. The compute server (Microway, Inc.) is a cluster computer containing 64 Intel Pentium III microprocessors and 16 GB of memory organized into 32 nodes connected by 100 Mb Ethernet. The visualization workstation (Sun Microsystems) is a workstation with one 900 MHz UltraSPARC-III microprocessor, 1 GB of memory, and the intermediate level of Sun's three levels of 3-D graphics hardware accelerators.This equipment will support 3 projects which concern computational mathematics including multi-dimensional quadratures, transforms, and numerical optimization. The unifying theme is numerical optimization, especially global optimization. The projects are divided according to application and include 3-D reconstruction problems in structural biology and systems design problems for nonlinear communication channels. The main application is structural biology, in particular, the structural biology of viruses. The problems of particular interest are 3-D signal reconstruction problems for computing the dynamical behavior of viruses from a variety of biophysical measurements.