Chiral Porous Materials for Enantioselective Catalysis and Separations

这项由化学学部先进材料项目（MPS）和化学传输系统学部动力学、催化和分子项目（ENG）联合授予北卡罗来纳大学教堂山分校的奖项旨在设计和合成基于聚合物-金属配位网络的多孔手性晶体和非晶体沸石材料。林教授将利用现有的2,2'-二羟基-1,1'-二萘制备各种具有不同官能团和拓扑结构的对映纯刚性和桥接配体。这些手性多孔材料将具有可定制的纳米级手性袋和功能，可用于对映选择性分离和催化的潜在应用。这些材料既有非均相催化剂的优点（包括催化剂分离和回收方便、稳定性高、易于操作），也有均相催化剂的优点（包括活性位点均匀、效率高、可重复性好、选择性好、可控性好、反应条件温和）。此外，材料化学方面的培训将提供给该奖项的各种学生。有了这个奖项，多孔和非晶体的类似沸石的材料，具有可定制的纳米级手性口袋和功能，将从现成的化学物质中合成，这些材料有望在对映选择性分离和催化手性药物和精细化学品的合成中得到应用。此外，这些催化剂将同时具有多相催化剂和均相催化剂的优点。

This joint award made to University of North Carolina Chapel Hill by the Advanced Materials Program in the Division of Chemistry (MPS) and the Kinetics, Catalysis and Molecular program in the Division of Chemical Transport System (ENG) is to design and synthesize porous chiral crystalline and non-crystalline zeolitic materials based on polymer-metal coordination networks. With this award, Professor Lin will prepare a variety of enantiopure rigid and bridging ligands with different functional groups and topologies from readily available 2,2'-dihydroxy-1,1'-binaphthalene. These chiral porous materials will have tailorable nanometer-sized chiral pockets and functionalities that can be exploited for potential applications in enantioselective separations and catalysis. These materials will have both the advantages offered by heterogeneous catalysts (including facile catalyst separation and recovery, high stability, and ease of handling), and those offered by their homogeneous counterparts (including homogeneity of active sites, high efficiency, reproducibility, selectivity, and controllability, and mild reaction conditions). In addition, training in materials chemistry will be provided to a diversity of students with this award. With this award, porous and non-crystalline zeolite like materials with tailorable nanometer-sized chiral pockets and functionalities will be synthesized from readily available chemicals, and these materials are expected to have applications in enantioselective separations and catalysis for the synthesis of chiral drugs and fine chemicals. In addition, these catalysts will have the advantages of both heterogeneous and homogeneous catalysts.