Geography-Based Exposure Assessment for Urban Metals
基于地理的城市金属暴露评估
基本信息
- 批准号:0221949
- 负责人:
- 金额:$ 42万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:2002
- 资助国家:美国
- 起止时间:2002-09-01 至 2004-02-29
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Although lead is a naturally occurring element present in many parts of the environment, human activities have dramatically increased lead levels in many locales, especially older parts of urban areas. Whereas lead normally constitutes about 0.002 percent of the Earth's crust, in cities, soil lead levels can be from five to 25 times as great. The heightened presence of lead translates into significantly increased exposure to lead contamination among urban residents, especially children. The average background lead level of the U.S. population is 2.8 micrograms per deciliter, but in many cities, substantial numbers of children have baseline blood lead levels in excess of 10 micrograms per deciliter. This research project will develop new methods for exploring spatial dimensions of pediatric lead poisoning. A multidisciplinary investigative team will study spatial relationships among urban environmental contaminants, the biogeochemical processes of their origin in soils and dust, and the potential for adverse public health risks associated with human exposure to them. A primary goal of this project is to quantitatively assess the community health risks associated with exposure to soils and interior household dusts that have been contaminated by heavy metals. A second major goal is to determine the feasibility of carrying out such assessments through the use of non-intrusive, ecological techniques. To accomplish these goals, the investigators will develop a geography-based lead-exposure assessment model for Syracuse, New York. Inputs to this model will be the blood lead monitoring results, population and housing census data, heavy-metal measurements for soils and dust, and other georeferenced data.This research will make a number of contributions to the spatial analysis literature. For example, it will extend small area estimation techniques to a nesting situation and establish a trade-off curve between effective sample size and accuracy/precision of sample statistics. It will improve understanding of geographic dimensions of lead dispersal, and it will test new approaches for monitoring contamination. This project also will have a significant policy impacts for the public health arena. In particular, it will provide a widely applicable, cost-effective, childhood lead poisoning assessment tool for urban environments; it will foster a geographically explicit interpretive framework for evaluating intervention measures; and it will help contribute to improvements in EPA exposure modeling capabilities.
虽然铅是一种自然存在的元素,存在于环境的许多部分,但人类活动大大增加了许多地方的铅水平,特别是城市地区的老旧地区。铅通常只占地壳的0.002%,而在城市里,土壤中的铅含量可能是地壳的5到25倍。铅含量的增加意味着城市居民,特别是儿童接触铅污染的机会大大增加。美国人口的平均背景铅含量为每分升2.8微克,但在许多城市,大量儿童的基线血铅水平超过每分升10微克。本研究项目将开发探索儿童铅中毒空间维度的新方法。一个多学科调查小组将研究城市环境污染物之间的空间关系、它们在土壤和灰尘中起源的生物地球化学过程,以及与人类接触这些污染物有关的潜在不利公共健康风险。该项目的一个主要目标是定量评估与接触受重金属污染的土壤和室内家庭粉尘有关的社区健康风险。第二个主要目标是确定通过使用非侵入性生态技术进行这种评估的可行性。为了实现这些目标,研究人员将为纽约州锡拉丘兹市开发一个基于地理位置的铅暴露评估模型。该模型的输入将是血铅监测结果、人口和住房普查数据、土壤和灰尘的重金属测量以及其他地理参考数据。本研究将对空间分析文献做出一定的贡献。例如,它将小面积估计技术扩展到嵌套情况,并在有效样本大小和样本统计的准确性/精度之间建立权衡曲线。它将增进对铅扩散的地理层面的了解,并将测试监测污染的新方法。该项目还将对公共卫生领域产生重大的政策影响。特别是,它将为城市环境提供一种广泛适用的、具有成本效益的儿童铅中毒评估工具;它将为评价干预措施建立一个地理上明确的解释框架;这将有助于改善环境保护局的暴露建模能力。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Daniel Griffith其他文献
Denoising a model employing automated bandwidth selection procedures and pre-whitened Euclidean- based quadratic surrogates in PROC ARIMA for optimizing asymptotic expansions and simulations of onchocerciasis endemic transmission zones in Burkina Faso
使用 PROC ARIMA 中的自动带宽选择程序和预白化的基于欧几里得的二次代理对模型进行去噪,以优化布基纳法索盘尾丝虫病流行传播区的渐近扩展和模拟
- DOI:
10.5897/jphe2013.0629 - 发表时间:
2014 - 期刊:
- 影响因子:0
- 作者:
B. Jacob;Robert J. Novak;L. Toe;Moussa S. Sanfo;R. Tingueria;Alain B Paré;Mounkaila Noma;Daniel Griffith;T. Unnasch - 通讯作者:
T. Unnasch
High throughput measurements of direct activation domain-coactivator interactions
- DOI:
10.1016/j.bpj.2022.11.576 - 发表时间:
2023-02-10 - 期刊:
- 影响因子:
- 作者:
Nicole DelRosso;Peter Suzuki;Daniel Griffith;Alex S. Holehouse;Lacramioara Bintu;Polly Fordyce - 通讯作者:
Polly Fordyce
LOCATE reveals electrostatic “islands” and “hotspots” are important for a disordered clock protein's interactions to regulate clock robustness
- DOI:
10.1016/j.bpj.2021.11.1731 - 发表时间:
2022-02-11 - 期刊:
- 影响因子:
- 作者:
Meaghan S. Jankowski;Daniel Griffith;Divya G. Shastry;Jacqueline F. Pelham;Joshua Thomas;Pankaj Karande;Alex S. Holehouse;Jennifer M. Hurley - 通讯作者:
Jennifer M. Hurley
Implementing Approximations to Extreme Eigenvalues and Eigenvalues of Irregular Surface Partitionings for Use in SAR and CAR Models
- DOI:
10.1016/j.proenv.2015.05.013 - 发表时间:
2015-01-01 - 期刊:
- 影响因子:
- 作者:
Daniel Griffith;Roger Bivand;Yongwan Chun - 通讯作者:
Yongwan Chun
A critical study of a 100-year-old patient receiving a dynamic hip screw
- DOI:
10.1016/j.joon.2007.08.001 - 发表时间:
2007-08-01 - 期刊:
- 影响因子:
- 作者:
Daniel Griffith - 通讯作者:
Daniel Griffith
Daniel Griffith的其他文献
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{{ truncateString('Daniel Griffith', 18)}}的其他基金
Determining Qualitative Geographic Sample Size in the Presence of Spatial Autocorrelation
在存在空间自相关的情况下确定定性地理样本量
- 批准号:
1262717 - 财政年份:2013
- 资助金额:
$ 42万 - 项目类别:
Standard Grant
Geography-Based Exposure Assessment for Urban Metals
基于地理的城市金属暴露评估
- 批准号:
0552588 - 财政年份:2005
- 资助金额:
$ 42万 - 项目类别:
Continuing Grant
COLLABORATIVE RESEARCH: APPROXIMATING EIGENSYSTEMS OF MATRICES USED IN SPATIAL ANALYSIS
合作研究:空间分析中使用的矩阵本征系统的近似
- 批准号:
0611883 - 财政年份:2005
- 资助金额:
$ 42万 - 项目类别:
Standard Grant
COLLABORATIVE RESEARCH: APPROXIMATING EIGENSYSTEMS OF MATRICES USED IN SPATIAL ANALYSIS
合作研究:空间分析中使用的矩阵本征系统的近似
- 批准号:
0435714 - 财政年份:2004
- 资助金额:
$ 42万 - 项目类别:
Standard Grant
Geography-Based Exposure Assessment for Urban Metals
基于地理的城市金属暴露评估
- 批准号:
0400559 - 财政年份:2003
- 资助金额:
$ 42万 - 项目类别:
Continuing Grant
An Ordinary Least Squares (OLS) Solution to Handling Spatial Autocorrelation Latent in Georeferenced Data
处理地理参考数据中潜在空间自相关的普通最小二乘 (OLS) 解决方案
- 批准号:
9905213 - 财政年份:1999
- 资助金额:
$ 42万 - 项目类别:
Continuing Grant
Uncovering Relationships Between Geo-Statistical and Spatial Autoregressive Modelling
揭示地理统计和空间自回归建模之间的关系
- 批准号:
9507855 - 财政年份:1995
- 资助金额:
$ 42万 - 项目类别:
Standard Grant
Computationally Simplified Estimators for Spatial Autoregressive Models
空间自回归模型的计算简化估计器
- 批准号:
9122232 - 财政年份:1992
- 资助金额:
$ 42万 - 项目类别:
Standard Grant
Collaborative Research on the Importance of Spatial Effects in Applied Regression Analysis in Regional Science and Geography
区域科学与地理学应用回归分析中空间效应重要性的合作研究
- 批准号:
8722086 - 财政年份:1988
- 资助金额:
$ 42万 - 项目类别:
Standard Grant
NATO Conference on Transformations Through Space and Time; Denmark, August 3-14, 1985.
北约空间和时间转型会议;
- 批准号:
8508460 - 财政年份:1985
- 资助金额:
$ 42万 - 项目类别:
Standard Grant
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