Capillary Sequencer for the George Washington University Campus

该合同支持购买一台八毛细管自动测序仪、一台聚合酶链式反应热循环仪以及DNA序列测定和后续分析所需的相关设备。这些仪器将被用来创建一个测序设施，供该大学生物科学系的教职员工和学生使用。预计的用途包括一系列不同的研究项目，包括蜘蛛、植物和脊椎动物的系统学；免疫系统的进化；植物信号网络；以及植物系统发育。在细胞和分子生物学中，序列数据对于分析基因结构和表达，以及预测、表征和操纵蛋白质的功能是至关重要的。序列数据在系统生物学中也很重要，在系统生物学中，DNA数据与形态数据一起用于了解生物之间的系统发育关系。这些设备将可用于研究和培训。除了教师和研究生研究人员外，进行独立研究或实验室练习的本科生将能够使用这些仪器。

The award supports the purchase of an automated, eight-capillary sequencer, a PCR thermal cycler, and associated equipment needed for DNA sequence determination and subsequent analysis. The instruments will be used create a sequencing facility for use by faculty and students in the University's Department of Biological Sciences. Anticipated uses include a diverse array of research projects including systematics of spiders, plants and vertebrates; evolution of the immune system; plant signaling networks; and plant phylogeny. Sequence data are of central importance for analyzing gene structure and expression, and for predicting, characterizing and manipulating protein function in cellular and molecular biology. Sequence data are also important in systematic biology where DNA data are used with morphological data to understand the phylogenetic relationships among organisms. The equipment will be available for use in both research and training. In addition to faculty and postgraduate researchers, undergraduate students doing independent research or laboratory exercises will be able to use the instruments.