Engineering Research Equipment: Ultrafast Laser System for Microscale Radiation Transport Studies

工程研究设备：用于微尺度辐射传输研究的超快激光系统

• 批准号: 0318001
• 负责人: Zhixiong Guo
• 金额: $ 6.65万
• 依托单位: Rutgers University New Brunswick
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2004-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0318001&HistoricalAwards=false
• 关键词: Engineering; Research; Equipment; Ultrafast; Laser

An award has been made toward the purchase of a femtosecond Ti:sapphire laser system. The equipment will be utilized in support of innovative research addressing emerging nanotechnology and bioimaging applications. Specifically, the requested equipment is necessary for the proposed experiments in developing a subsurface imaging method with temporal log-slope analysis for noninvasive detection of small breast tumors, a two-photon fluorescence microscopy system for investigation of drug delivery and oxidative stress in skins, and a nanoscale sensing system for time-resolved detection of adsorption or attachment of nanoscopic entities to a surface. The subsurface imaging method is original and does not require complicated inverse design. The study is aimed at enabling real time clinical use of diffuse optical tomography. The broad impacts of the proposed research include a boost to interdisciplinary research at Rutgers and the development of capabilities of the PI in several emerging areas, including biotechnology. The laser system will enhance a collaborative arrangement that has been established with Bell Labs. The equipment will also be very useful for the training of graduate students in the operation and applications of state-of-the-art ultrafast laser systems, and for introducing undergraduate students to interdisciplinary topics of research. It is also a valuable addition to the research infrastructure at Rutgers University.

已授予购买飞秒钛：蓝宝石激光系统的合同。这些设备将用于支持针对新兴纳米技术和生物成像应用的创新研究。具体而言，所要求的设备是必要的拟议的实验，在开发一个亚表面成像方法与时间的对数斜率分析的非侵入性检测小乳腺肿瘤，双光子荧光显微镜系统的药物输送和皮肤中的氧化应激的调查，和纳米级传感系统的时间分辨检测的吸附或附着的纳米级实体的表面。 地下成像方法具有独创性，不需要复杂的反求设计。该研究旨在使真实的时间临床使用的扩散光学断层扫描。 拟议研究的广泛影响包括推动罗格斯大学的跨学科研究，以及PI在包括生物技术在内的几个新兴领域的能力发展。激光系统将加强与贝尔实验室建立的合作安排。该设备也将是非常有用的培训研究生的操作和应用最先进的超快激光系统，并为本科生介绍跨学科的研究课题。 这也是罗格斯大学研究基础设施的一个有价值的补充。