MRI: Acquisition of a Multi-User System for the Direct Excitation of Lanthanide (III) Luminescence for Biological, Inorganic, and Materials Chemistry

MRI：获取用于生物、无机和材料化学直接激发镧系元素 (III) 发光的多用户系统

• 批准号: 0321058
• 负责人: Janet Morrow
• 金额: $ 17.55万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0321058&HistoricalAwards=false
• 关键词: MRI; Acquisition; Multi; User; System

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at SUNY-Buffalo will acquire a multi-user laser system for the direct excitation of lanthanide (Ln) (III) luminescence for biological, inorganic, and materials chemistry. This equipment will enhance research in the following areas: a) protein-doped xerogels; b) solvation of Ln(III) ions in room temperature ionic liquids; c) Ln(III) polyoxometalates as building blocks for new materials; d) de novo artificial nucleases basded on helix-turn-helix DNA-binding motifs; e) Ln(III) complex catalysts; and f) Ln(III) probes for metal ion RNA interactions. This instrumentation will be used not only by faculty at the University at Buffalo, but also researchers at the University of Iowa and Hunter College. These studies will use Ln(III) luminescence to study materials and catalysts and probe metal ion binding sites in proteins and nucleic acids; therefore, they will have an impact in numerous fields, including materials chemistry and biochemistry .

凭借主要研究仪器（MRI）计划的这一奖项，纽约州立大学布法罗分校的化学系将获得一个多用户激光系统，用于直接激发生物，无机和材料化学的镧系元素（Ln）（III）发光。这一设备将加强以下领域的研究：（a）掺杂蛋白质的干凝胶;（B）室温离子液体中Ln（III）离子的溶剂化;（c）作为新材料构件的Ln（III）聚氧乙烯酸盐;（d）基于螺旋-转角-螺旋DNA结合基序的从头人工核酸酶;（e）Ln（III）复合催化剂;（f）用于金属离子RNA相互作用的Ln（III）探针。这种仪器不仅将被布法罗大学的教师使用，而且还将被爱荷华州大学和亨特学院的研究人员使用。 这些研究将使用Ln（III）发光来研究材料和催化剂，并探测蛋白质和核酸中的金属离子结合位点;因此，它们将在许多领域产生影响，包括材料化学和生物化学。