Novel roles and mechanisms of action of the ABI3 transcription factor and its interactors as 'gatekeeper' during the plant lifecycle and in stress conditions in conifers and angiosperms

ABI3转录因子及其相互作用子在植物生命周期和针叶树和被子植物逆境条件下作为“看门人”的新作用和作用机制

• 批准号: 164715378
• 负责人: Dr. Kerstin Müller
• 金额: --
• 依托单位: Department of Biological Sciences
• 依托单位国家: 德国
• 项目类别: Research Fellowships
• 财政年份: 2009
• 资助国家: 德国
• 起止时间: 2008-12-31 至 2010-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/164715378?language=en
• 关键词: Novel; roles; mechanisms; action; ABI3

ABI3 proteins are transcription factors that act as intermediaries in regulating the response to the plant hormone ABA. The proposed research is based on the hypothesis that ABI3 acts together with AIPs (ABi3 Interacting Proteins) to regulate key transitions during the plant lifecycle in conifers and angiosperms, including the transition from seed development to germination and seedling growth and from vegetative growth to bud dormancy and subsequent bud burst. ABI3 may maintain the current developmental stage and prevent plants from entering the next stage prematurely, with distinct AIP action depending on the developmental stage. In addition, ABI3 may play an important role in sensing of and reaction to abiotic stress. The proposed project will look at mechanisms underlying these multiple functions of ABI3. The objectives of this project are to investigate (1) the role and mechanisms of ABI3 and its interactors in regulating important transitions of the plant lifecycle, (2) the role of ABI3 and its interactors as a safeguard in stress conditions and (3) the role of ABI3 in setting the epigenetic status of target genes. This research will uncover novel findings at a mechanistic level of the role of ABI3 in plants and will have significance to forestry and agriculture, where seed quality, seedling vigour and the ability to resist stress as well as an understanding of bud dormancy are of utmost importance.

ABI3蛋白是转录因子，其在调节对植物激素阿坝的反应中充当中间体。这项研究基于这样的假设，即ABI3与AIPs（ABi3相互作用蛋白）一起调节针叶树和被子植物生命周期中的关键转变，包括从种子发育到萌发和幼苗生长以及从营养生长到芽休眠和随后的芽萌发的转变。ABI3可以维持当前的发育阶段并防止植物过早进入下一个阶段，根据发育阶段具有不同的AIP作用。此外，ABI3可能在非生物胁迫的感知和反应中发挥重要作用。拟议的项目将着眼于ABI3这些多重功能的机制。本项目的目标是研究（1）ABI3及其互作因子在调节植物生命周期重要转变中的作用和机制，（2）ABI3及其互作因子在胁迫条件下作为保护措施的作用，以及（3）ABI3在设定靶基因表观遗传状态中的作用。这项研究将揭示ABI3在植物中作用的机制水平的新发现，并将对林业和农业具有重要意义，其中种子质量，幼苗活力和抗胁迫能力以及对芽休眠的理解至关重要。