Digital Fish Library

数字鱼类图书馆

• 批准号: 0446389
• 负责人: Lawrence Frank
• 金额: $ 246.51万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0446389&HistoricalAwards=false
• 关键词: Digital; Fish; Library

The University of California at San Diego is awarded a grant to digitize a representative sample of the Marine Vertebrates Collection (MVC) at the Scripps Institution of Oceanography (SIO), among the largest and most comprehensive collections of its kind in the world. It is a significant research resource for many scientists and also holds great potential as an educational resource. However, long-term maintenance of specimen integrity is often in conflict with specimen usage (e.g., dissection) and transfer of specimens is costly and involves potential risk to specimens. Moreover, accessibility to the MVC is necessarily restricted, limiting the potential scope of educational uses. Magnetic resonance imaging (MRI) is unique in its ability to non-invasively acquire high-resolution 3- dimensional (3D) digital data from soft tissue structures. Recent collaborative work between the UCSD Center for Functional MRI (CFMRI) and researchers at SIO has shown that MRI can effectively be used to non-invasively visualize and quantify the internal anatomy of fishes, and can potentially increase the effectiveness of both the research and educational uses of the MVC. In this award Digital Fish Library (DFL) will be developed that includes 1. Collection of high-resolution 3D MRI images of specimens that cover the range of morphological diversity in fishes with special emphasis on the strengths of the MVC; 2. Development of a public DFL web site for data retrieval, visualization, and quantitative analysis of the MRI data from the MVC, including integration of the data with extant databases and with data collected from other methodologies; 3. Development, in collaboration with the Birch Aquarium at Scripps (BAS), of the Digital Dissection Tool (DDT), an educational program embedded within the DFL site. Aimed at high-school science students, it uses the MRI data from the MVC and the image analysis tools within the DFL, and is supplemented by educational modules on the basic scientific areas involved in the DFL. This tool will be tested in the Academic Connections Program (ACP), a college preparatory high school level curriculum run through UCSD. Successful completion of this project will establish a digital library of approximately 1000 MVC specimens available to researchers, students, and educators on the internet for quantitative analysis, visualization, or bioinformatics purposes. In addition, an educational tool will be produced that is appropriate for high school students and above for learning about fish anatomy, MRI, bioinformatics, and the application of digital image analysis methods to marine biology.

加州大学圣地亚哥分校获得了一项拨款，用于对斯克里普斯海洋学研究所 (SIO) 的海洋脊椎动物馆藏 (MVC) 的代表性样本进行数字化，该馆藏是世界上同类馆藏中规模最大、最全面的。对于许多科学家来说，它是重要的研究资源，并且作为教育资源也具有巨大的潜力。然而，标本完整性的长期维护通常与标本的使用（例如解剖）相冲突，并且标本的转移成本高昂并且涉及标本的潜在风险。此外，MVC 的可访问性必然受到限制，从而限制了教育用途的潜在范围。磁共振成像 (MRI) 的独特之处在于其能够以非侵入方式从软组织结构获取高分辨率 3 维 (3D) 数字数据。加州大学圣地亚哥分校功能 MRI 中心 (CFMRI) 和 SIO 研究人员最近的合作表明，MRI 可以有效地用于非侵入性地可视化和量化鱼类的内部解剖结构，并有可能提高 MVC 研究和教育用途的有效性。在该奖项中，将开发数字鱼类库 (DFL)，其中包括 1. 收集高分辨率 3D MRI 样本图像，涵盖鱼类形态多样性的范围，特别强调 MVC 的优势； 2. 开发一个公共 DFL 网站，用于对来自 MVC 的 MRI 数据进行数据检索、可视化和定量分析，包括将数据与现有数据库以及从其他方法收集的数据集成； 3. 与斯克里普斯伯奇水族馆 (BAS) 合作开发数字解剖工具 (DDT)，这是嵌入在 DFL 站点中的教育程序。它针对高中理科学生，使用来自 MVC 的 MRI 数据和 DFL 内的图像分析工具，并辅以 DFL 涉及的基础科学领域的教育模块。该工具将在学术联系计划 (ACP) 中进行测试，这是加州大学圣地亚哥分校运营的大学预科高中水平课程。该项目的成功完成将建立一个包含约 1000 个 MVC 标本的数字图书馆，供研究人员、学生和教育工作者在互联网上进行定量分析、可视化或生物信息学目的。此外，还将制作适合高中生及以上学生学习鱼类解剖学、MRI、生物信息学以及数字图像分析方法在海洋生物学中的应用的教育工具。

项目成果

Evidence for cranial endothermy in the opah (Lampris guttatus)

• DOI: 10.1242/jeb.022814
• 发表时间: 2009-02-15
• 期刊: JOURNAL OF EXPERIMENTAL BIOLOGY
• 影响因子: 2.8
• 作者: Runcie, Rosa M.;Dewar, Heidi;Dickson, Kathryn A.
• 通讯作者: Dickson, Kathryn A.

Cranial endothermy and a putative brain heater in the most basal tuna species, Allothunnus fallai

• DOI: 10.1111/j.1095-8649.2007.01446.x
• 发表时间: 2007-06
• 期刊: Journal of Fish Biology
• 影响因子: 2
• 作者: C. Sepulveda;K. Dickson;L. Frank;J. Graham

Brain Size and Brain Organization of the Whale Shark, Rhincodon typus, Using Magnetic Resonance Imaging

使用磁共振成像研究鲸鲨（犀牛鲨）的大脑大小和大脑组织

• DOI: 10.1159/000235962
• 发表时间: 2009
• 期刊: Behavior and Evolution
• 作者: Yopak, Kara E.;Frank, Lawrence R.
• 通讯作者: Frank, Lawrence R.

Utilizing magnetic resonance imaging (MRI) to assess the effects of angling-induced barotrauma on rockfish (Sebastes)

利用磁共振成像 (MRI) 评估钓鱼引起的气压伤对石斑鱼 (Sebastes) 的影响

• DOI: 10.1139/f08-102
• 发表时间: 2008
• 期刊: Canadian Journal of Fisheries and Aquatic Sciences
• 影响因子: 2.4
• 作者: Rogers, Bonnie L.;Lowe, Christopher G.;Fernández-Juricic, Esteban;Frank, Lawrence R.
• 通讯作者: Frank, Lawrence R.

Spiracular air breathing in polypterid fishes and its implications for aerial respiration in stem tetrapods

• DOI: 10.1038/ncomms4022
• 发表时间: 2014-01-01
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Graham, Jeffrey B.;Wegner, Nicholas C.;Long, John A.
• 通讯作者: Long, John A.