IGERT in Chemical Genomics: Forging Complementation at the Interface of Chemistry, Engineering, Computational Sciences and Cell Biology

该综合研究生教育和研究培训（IGERT）奖将在加州大学滨江（UCR）建立先进化学基因组学（ChemGen）博士培训计划。该计划的目标是培养一批科学家，他们对细胞生物学，化学，计算科学和工程等学科有着深入和广泛的理解，并有能力进行旨在解决生物学中复杂问题的合作研究。该计划将为毕业生提供多学科研究技能，敏锐地意识到他们的发现解决全球食品，健康和环境问题的潜力，他们的研究的伦理影响，并接触到学术界和工业界的各种研究环境。具体而言，学生将接受先进的化学基因组学培训-这是一个将创新的高通量化学筛选，化学配体分析，化学合成与遗传，基因组学，生物信息学工具和纳米级工程相结合的领域-以解决细胞生物学的挑战。该研究生项目的协调实体是植物细胞生物学中心，该中心建立在UCR的植物和真菌细胞生物学，生物工程，化学和计算生物学的基础上。ChemGen博士生将有两名共同导师，代表两个学科。使用化学基因组学方法来解决生物学问题的研究项目将为联合有效的多学科团队提供独特的机会。丰富的博士培训计划将包括化学基因组学的设计项目工作室，每周一次的研讨会/讨论组，促进跨学科交流的年度务虚会，与代表性不足的本科生互动，以及工业或学术实习。 该计划的更广泛的影响包括毕业生谁可以利用他们的发现来解决全球食品，健康和环境问题。

This Integrative Graduate Education and Research Training (IGERT) award will establish a doctoral training program in advanced chemical genomics (ChemGen) at the University of California, Riverside (UCR). The goal of the program is to prepare a cohort of scientists with depth and breadth of understanding across the disciplines of cell biology, chemistry, computational sciences and engineering, with competence in collaborative research aimed at solving complex problems in biology. The program will prepare graduates with skills for multidisciplinary research, acute awareness of the potential for their discoveries to address global food, health and environmental problems, of the ethical implications of their research, and with exposure to a variety of research environments in academia and industry. Specifically, students will be trained in advanced chemical genomics - a field that integrates innovative high-throughput chemical screens, chemical-ligand analyses, chemical synthesis with genetic, genomic, bioinformatic tools and nanoscale engineering - to solve challenges in cell biology. The coordinating entity for this graduate project is the Center for Plant Cell Biology, which builds upon strengths in plant and fungal cell biology, bioengineering, chemistry and computational biology at UCR. ChemGen doctoral students will have two co-mentors, representing two disciplines. Research projects that use a chemical genomics approach to address biological questions will provide a unique opportunity to unite effective multidisciplinary teams. The enriched doctoral training program will include a design project studio in chemical genomics, a weekly seminar/discussion group, an annual retreat fostering communication across disciplines, interaction with underrepresented undergraduates, and an industrial or academic internship. Broader impacts of the program include perparation of graduates who can utilize their discoveries to address global food, health, and environmental problems.