IGERT in Chemical Genomics: Forging Complementation at the Interface of Chemistry, Engineering, Computational Sciences and Cell Biology

这一综合性研究生教育和研究培训(IGERT)奖将在加州大学河滨分校(UCR)建立高级化学基因组学(ChemGen)博士培训计划。该项目的目标是培养一批在细胞生物学、化学、计算科学和工程学领域具有深度和广度理解的科学家，他们具有合作研究的能力，旨在解决生物学中的复杂问题。该项目将使毕业生具备多学科研究的技能，敏锐地意识到他们的发现可能解决全球食品、健康和环境问题，了解他们研究的伦理影响，并接触到学术界和工业界的各种研究环境。具体地说，学生将接受先进化学基因组学的培训-这是一个将创新的高通量化学筛选、化学配体分析、化学合成与遗传、基因组、生物信息工具和纳米工程相结合的领域-以解决细胞生物学中的挑战。这个毕业项目的协调机构是植物细胞生物学中心，该中心在植物和真菌细胞生物学、生物工程、化学和计算生物学方面具有优势。ChemGen博士生将有两名共同导师，代表两个学科。使用化学基因组学方法解决生物学问题的研究项目将提供一个独特的机会，以联合有效的多学科团队。丰富的博士培训计划将包括一个化学基因组学设计项目工作室，每周一次研讨会/讨论小组，促进跨学科交流的年度务虚会，与未被充分代表的本科生互动，以及工业或学术实习。该计划的更广泛影响包括改善那些能够利用他们的发现来解决全球食品、健康和环境问题的毕业生。

This Integrative Graduate Education and Research Training (IGERT) award will establish a doctoral training program in advanced chemical genomics (ChemGen) at the University of California, Riverside (UCR). The goal of the program is to prepare a cohort of scientists with depth and breadth of understanding across the disciplines of cell biology, chemistry, computational sciences and engineering, with competence in collaborative research aimed at solving complex problems in biology. The program will prepare graduates with skills for multidisciplinary research, acute awareness of the potential for their discoveries to address global food, health and environmental problems, of the ethical implications of their research, and with exposure to a variety of research environments in academia and industry. Specifically, students will be trained in advanced chemical genomics - a field that integrates innovative high-throughput chemical screens, chemical-ligand analyses, chemical synthesis with genetic, genomic, bioinformatic tools and nanoscale engineering - to solve challenges in cell biology. The coordinating entity for this graduate project is the Center for Plant Cell Biology, which builds upon strengths in plant and fungal cell biology, bioengineering, chemistry and computational biology at UCR. ChemGen doctoral students will have two co-mentors, representing two disciplines. Research projects that use a chemical genomics approach to address biological questions will provide a unique opportunity to unite effective multidisciplinary teams. The enriched doctoral training program will include a design project studio in chemical genomics, a weekly seminar/discussion group, an annual retreat fostering communication across disciplines, interaction with underrepresented undergraduates, and an industrial or academic internship. Broader impacts of the program include perparation of graduates who can utilize their discoveries to address global food, health, and environmental problems.