Comparative genome-scale analyses of submergence and anaerobic germination mechanisms in rice and maize

水稻和玉米淹没和厌氧发芽机制的比较基因组规模分析

• 批准号: 1121626
• 负责人: Julia Bailey-Serres
• 金额: $ 70万
• 依托单位: University of California-Riverside
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1121626&HistoricalAwards=false
• 关键词: Comparative; genome; scale; analyses; submergence

Flooding events significantly damage agricultural production in the US and elsewhere. The development of crop cultivars that can survive short-term flooding can help stabilize and increase food production. The recent recognition of rice varieties tolerant to short-term flooding has led to the identification of the submergence tolerance regulator gene called SUB1A. The precise genetic characterization of SUB1A has allowed breeders to develop new high-yielding rice varieties with submergence tolerance that are now grown in flood-prone fields of South and Southeast Asia. This project will continue the molecular characterization of SUB1A and seek new submergence regulators that act earlier in development. Rice plants that can survive flooding during seed germination can reduce labor cost and herbicide use. The effectiveness of combining SUB1A with the recently identified ANAEROBIC GERMINATION 1 (AG1) gene will be explored in rice. Additionally, the characterization of molecular responses to flooding will be extended to corn, a vital grain crop that is flooding sensitive. These analyses will examine genetic variation in anaerobic germination and submergence tolerance in maize as well as profile and manipulate molecular responses to these stresses. The results will provide a greater understanding of sensing, signaling and response mechanisms to flooding during seed germination and vegetative growth in rice and maize. The research will be carried out at a Hispanic Serving institution. Postdoctoral, graduate, and undergraduate researchers will receive cross-disciplinary training in physiology, molecular biology, analytical chemistry and systems biology in a multicultural laboratory and institute environment. The development and dissemination of a science-learning module will allow 8th graders, many from underrepresented groups, at Title I schools to participate in hands-on science experiments demonstrating the significance of plant biology research on food security and sustainable agriculture. The knowledge obtained from this project will favorably impact food, feed and fuel production in the US and elsewhere.

洪水事件严重损害了美国和其他地方的农业生产。培育能够在短期洪水中存活的作物品种有助于稳定和增加粮食产量。最近认识到水稻品种耐短期水浸导致被称为SUB1A的耐淹调节基因的鉴定。SUB1A的精确遗传特性使育种者能够开发出具有耐淹性的新的高产水稻品种，这些品种目前已在南亚和东南亚的洪水易发地区种植。该项目将继续SUB1A的分子表征，并寻求在开发早期起作用的新的淹没调节剂。在种子发芽期间能够在洪水中存活的水稻植物可以减少劳动力成本和除草剂的使用。将SUB1A与最近鉴定的厌氧萌发1（AG 1）基因组合的有效性将在水稻中进行探索。此外，分子对洪水的反应的表征将扩展到玉米，一种对洪水敏感的重要粮食作物。这些分析将研究玉米厌氧萌发和耐淹性的遗传变异，以及对这些胁迫的分子反应。研究结果将有助于更好地理解水稻和玉米种子萌发和营养生长过程中对洪水的感知、信号和响应机制。这项研究将在西班牙裔服务机构进行。博士后，研究生和本科生研究人员将在多元文化的实验室和研究所环境中接受生理学，分子生物学，分析化学和系统生物学的跨学科培训。科学学习模块的开发和传播将允许8年级学生，许多来自代表性不足的群体，在标题I学校参加动手科学实验，展示植物生物学研究对粮食安全和可持续农业的重要性。从该项目中获得的知识将对美国和其他地方的食品、饲料和燃料生产产生有利影响。

项目成果

Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress

• DOI: 10.1105/tpc.19.00463
• 发表时间: 2019-11-01
• 期刊: PLANT CELL
• 影响因子: 11.6
• 作者: Lee, Travis A.;Bailey-Serres, Julia
• 通讯作者: Bailey-Serres, Julia