CAREER: Ultra Low Power Passive Microsystems for Medication Compliance Monitoring

职业：超低功耗无源微系统的药物合规性认证PI：Rizwan Bashirullah建议号：ECS-0547057摘要本职业建议的重点是超低功耗硅基无源微系统的开发，用于体内深层通信。体内通信无源器件概念的核心是使用新型功率调节电路从弱入射场收集RF能量，并使用高效电路拓扑从体内深处再辐射外部可检测的功率量。知识产权：这项研究将，（1）表征电压倍增器，以确定输入电压，泄漏，RF清除的可靠性和效率，（2）开发将导致放大器集成和隔离的片上多谐振无源结构，（3）评估和理解放大器和倍增器的相互作用，以及（4）使用人体生物幻象测试这些功率调节电路对体内信号的有效性（即具有与人体等效的电特性的溶液）。PI将建立在植入式集成电子器件的先前研究基础上，并使用先进的CMOS技术，在用于体内通信的微型无源器件的知识和创新方面取得根本性进展。更广泛的影响：具有集成RF子系统的微型无源设备的特定高影响工程应用是药物依从性监测，因为据估计，美国医疗保健系统每年因不依从药物治疗方案而造成的成本超过1000亿美元。拟议的计划旨在促进对多学科研究的兴趣，使研究生、本科生和高中生接触创新的集成电路技术。拟议的教育计划将强调代表性不足的群体通过具有理论和实验组成部分的教育模块参与高中一级的综合研究和学术方案。

CAREER: Ultra Low Power Passive Microsystems for Medication Compliance MonitoringPI: Rizwan BashirullahProposal No: ECS-0547057AbstractThis Career proposal focuses on the development of ultra low power silicon based passive microsystems for deep in-body communications. Central to the concept of in-body communication passive devices is the idea of RF energy scavenging from weak incident fields using novel power conditioning circuits and reradiating, from deep inside the body, externally detectable amounts of power using highly efficient circuit topologies.Intellectual Merit: This study will, (1) characterize voltage multipliers to determine fundamental tradeoffs in input voltage, leakage, reliability and efficiency for RF scavenging, (2) develop on-chip multi-resonant passive structures that will lead to amplifier integration and isolation, (3) evaluate and understand amplifier and multiplier interactions and (4) test the effectiveness of these power conditioning circuits for in-body signaling using human biological phantoms (i.e. solutions with equivalent electrical properties as the human body). The PI will build upon previous research in implantable integrated electronics and use advanced CMOS technology to bring forth fundamental advances in knowledge and innovation on miniature passive devices for in-body communications. Broader Impacts: A specific high-impact engineering application of a miniature passive device with integrated RF subsystem is in medication compliance monitoring, as it is estimated that the annual cost to the U.S. healthcare system from non-compliance with medication regimens exceeds $100 billion. The proposed plan is intended to promote interest in multidisciplinary research that will provide graduate, undergraduate and high school students exposure to innovative integrated circuit technologies. The proposed educational plan will emphasize the participation of underrepresented groups at the high school level via educational modules with theoretical and experimental components in the integrated research and academic programs.