Elucidation of the signalling pathways during fertilization in mammals

阐明哺乳动物受精过程中的信号通路

• 批准号: DP0986217
• 负责人: Prof Keith Jones
• 金额: $ 22.53万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0986217
• 关键词: Elucidation; signalling; pathways; during; fertilization

This grant sets out to understand how the union of the sperm and egg at fertilization generates a viable embryo: this is a fundamental event in biology. We aim to understand the basic signalling pathways from the sperm which allow the egg to become an embryo and are known to influence embryo quality. They are therefore important in our understanding of what constitutes a healthy early start to life. Australia also has economic interests in understanding the reproductive process in aiding breeding programs for commercially important livestock and endangered species and contraception programs for pest populations.

这项资助旨在了解精子和卵子在受精时的结合如何产生一个可存活的胚胎：这是生物学中的一个基本事件。我们的目标是了解精子的基本信号通路，这些通路允许卵子成为胚胎，并且已知会影响胚胎质量。因此，它们对我们理解什么是健康的早期生活至关重要。澳大利亚也有经济利益，在了解生殖过程中，以帮助商业上重要的牲畜和濒危物种的育种计划和害虫种群的避孕计划。