Laser Engineered Multilayer Bioactive Coatings with Hydroxyapatite Nano-Powders

含有羟基磷灰石纳米粉末的激光工程多层生物活性涂层

基本信息

  • 批准号:
    0600739
  • 负责人:
  • 金额:
    $ 30万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2006
  • 资助国家:
    美国
  • 起止时间:
    2006-08-15 至 2006-07-31
  • 项目状态:
    已结题

项目摘要

The aim of this research program is to investigate a novel multiple-layer laser coating process to form functionally gradient bioceramic coatings on Ti6Al4V metal substrates. Application of bioactive ceramic coatings, such as Hydroxyapatite (HAp), is common in load bearing metal implants to improve cell-materials interaction and reduce healing time. However, most of the commercial coating processes present a sharp coating/substrate interface, which is always a potential source of weakness because severe stresses can build up due to the mismatch of mechanical properties and thermal expansion coefficients between the implant and coating material. This program seeks to overcome these problems with a laser engineered multilayer bioactive coating with HAp nano-powders in which a progressive change in both microstructure and properties over the interface will be attained. More specifically, the aims of this project are: (a) synthesis of nano-scale hydroxyapatite particles with tailored size and morphology using micelle and reverse micelle template systems; (b) processing of porous single and multiple-layer HAp/Ti coatings on Ti6Al4V substrate by pulsed laser surface engineering; and (c) characterization of physical, mechanical and biological properties. Process parameters will be optimized to achieve good bonding strength while maintaining phase purity and biocompatibility. The successful completion of this work will significantly improve the lifetime of bioceramic coatings. This work will increase the presence of nontraditional manufacturing (NTM) techniques in manufacturing education by establishing a strong research program involving laser manufacturing. Students will be recruited and encouraged to participate in this project through outreach activities for high school students and under-represented minorities.
本研究的目的是探索一种新的多层激光涂层工艺,在Ti6Al4V金属衬底上形成功能梯度生物陶瓷涂层。生物活性陶瓷涂层,如羟基磷灰石(HAP),在承重金属种植体中的应用是常见的,以改善细胞与材料的相互作用,缩短愈合时间。然而,大多数商业涂层工艺呈现出尖锐的涂层/基材界面,这始终是一个潜在的弱点,因为由于植入物和涂层材料之间的机械性能和热膨胀系数不匹配,可能会产生严重的应力。这项计划旨在克服这些问题,激光工程的多层生物活性涂层与羟基磷灰石纳米粉末,其中将实现在界面上的组织和性能的渐进变化。更具体地说,本项目的目标是:(A)利用胶束和反胶束模板系统合成尺寸和形貌可调的纳米羟基磷灰石颗粒;(B)利用脉冲激光表面工程技术在Ti6Al4V衬底上制备多孔的单层和多层HAP/Ti涂层;以及(C)物理、机械和生物性能的表征。将优化工艺参数,以在保持相纯度和生物相容性的同时获得良好的结合强度。这项工作的成功完成将大大提高生物陶瓷涂层的使用寿命。这项工作将通过建立一个涉及激光制造的强有力的研究计划,增加非传统制造(NTM)技术在制造业教育中的存在。将通过面向高中生和代表性不足的少数群体的外联活动,招募和鼓励学生参与这一项目。

项目成果

期刊论文数量(0)
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Gary Cheng其他文献

Fine-tuning in Federated Learning: a simple but tough-to-beat baseline
联邦学习的微调:一个简单但难以超越的基线
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Gary Cheng;Karan N. Chadha;John C. Duchi
  • 通讯作者:
    John C. Duchi
Collaboratively Learning Linear Models with Structured Missing Data
使用结构化缺失数据协作学习线性模型
  • DOI:
    10.48550/arxiv.2307.11947
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Chen Cheng;Gary Cheng;John C. Duchi
  • 通讯作者:
    John C. Duchi
A Decade of Sentic Computing: Topic Modeling and Bibliometric Analysis
  • DOI:
    10.1007/s12559-021-09861-6
  • 发表时间:
    2021-05-05
  • 期刊:
  • 影响因子:
    4.300
  • 作者:
    Xieling Chen;Haoran Xie;Gary Cheng;Zongxi Li
  • 通讯作者:
    Zongxi Li
Causal Inference out of Control: The Steerability of Consumption
失控的因果推理:消费的可控性
  • DOI:
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Gary Cheng;Moritz Hardt;Celestine Mendler
  • 通讯作者:
    Celestine Mendler
Learner engagement in digital game-based vocabulary learning and its effects on EFL vocabulary development
  • DOI:
    10.1016/j.system.2023.103173
  • 发表时间:
    2023-12-01
  • 期刊:
  • 影响因子:
  • 作者:
    Ruofei Zhang;Di Zou;Gary Cheng
  • 通讯作者:
    Gary Cheng

Gary Cheng的其他文献

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{{ truncateString('Gary Cheng', 18)}}的其他基金

EAGER: Laser Condensation of Graphene/Silicon Nanocomposites for Enhanced Electrochemical Properties
EAGER:激光凝聚石墨烯/硅纳米复合材料以增强电化学性能
  • 批准号:
    1741100
  • 财政年份:
    2017
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
High Throughput Magnetic Optical Nano-Milling of Thin Layer Materials with Designed Nano-Chisels
使用设计的纳米凿子对薄层材料进行高通量磁光纳米铣削
  • 批准号:
    1636101
  • 财政年份:
    2016
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
Large Scale Nanomanufacturing of Novel Inhomogeneous Strained Two-Dimensional Materials with Tunable Electronic and Optical Properties
具有可调谐电子和光学特性的新型非均匀应变二维材料的大规模纳米制造
  • 批准号:
    1538360
  • 财政年份:
    2015
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
Collaborative Research: Electromagnetic Peening Assisted Laser Micromachining (EPALM) - A Hybrid Micromachining Process with Enhanced Mechanical Properties
合作研究:电磁喷丸辅助激光微加工 (EPALM) - 一种具有增强机械性能的混合微加工工艺
  • 批准号:
    1000226
  • 财政年份:
    2010
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
Nanostructures Integrated Laser Shock Peening (nLSP) Processes and Their Mechanisms for Enhanced Fatigue Performance
纳米结构集成激光冲击强化 (nLSP) 工艺及其增强疲劳性能的机制
  • 批准号:
    0900327
  • 财政年份:
    2009
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
IDR/Collaborative Research: Manufacturing Functional Laminated Composites Structures on Patterned Uneven Three-Dimensional Surface
IDR/合作研究:在图案化不平坦三维表面上制造功能层压复合材料结构
  • 批准号:
    0928752
  • 财政年份:
    2009
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
CAREER: A Hybrid High Strain Rate Forming Process - Laser Dynamic Forming for Micro- and Meso- Scale 3D Shapes
职业:混合高应变率成形工艺 - 用于微米级和细观级 3D 形状的激光动态成形
  • 批准号:
    0809463
  • 财政年份:
    2007
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
Laser Engineered Multilayer Bioactive Coatings with Hydroxyapatite Nano-Powders
含有羟基磷灰石纳米粉末的激光工程多层生物活性涂层
  • 批准号:
    0650822
  • 财政年份:
    2007
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
Laser Engineered Multilayer Bioactive Coatings with Hydroxyapatite Nano-Powders
含有羟基磷灰石纳米粉末的激光工程多层生物活性涂层
  • 批准号:
    0802265
  • 财政年份:
    2007
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant
CAREER: A Hybrid High Strain Rate Forming Process -- Laser Dynamic Forming for Micro- and Meso- Scale 3D Shapes
职业:混合高应变率成形工艺——用于微米级和细观级 3D 形状的激光动态成形
  • 批准号:
    0710729
  • 财政年份:
    2006
  • 资助金额:
    $ 30万
  • 项目类别:
    Standard Grant

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