Excited State Dynamics of DNA Base-Pairs

DNA 碱基对的激发态动力学

• 批准号: 0615401
• 负责人: Mattanjah de Vries
• 金额: $ 52.4万
• 依托单位: University of California-Santa Barbara
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2010-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0615401&HistoricalAwards=false
• 关键词: Excited; State; Dynamics; DNA; Base

In this collaborative project, funded by the Experimental Physical Chemistry Program of the Chemistry Division, and by the Office of International Science and Education, Prof. Mattanjah deVries of the University of California, Santa Barbara and his graduate research students will study the photophysics of DNA base-pairs in the gas phase. In this work, Prof. deVries and his students will be collaborating with the theoretical chemistry group of Prof. Wolfgang Domcke at the Technical University of Munich. Prof. Domcke's group has support from the DFG for this work. A broader scientific impact of this research will come from the answers that it provides about the photostability of these species under the conditions of the early earth and how this may have affected the eventual chemical makeup of living systems. Besides the broader scientific impacts of the research being supported, Prof. de Vries will be providing his students with training in sophisticated experimental techniques and state-of-the-art theoretical methods. In addition, his students will gain valuable international experience through their collaboration with Prof. Domcke and his group.

在这个由化学学部实验物理化学项目和国际科学与教育办公室资助的合作项目中，加州大学圣巴巴拉分校的Mattanjah deVries教授和他的研究生将研究DNA碱基对在气相中的光物理学。在这项工作中，deVries教授和他的学生将与慕尼黑工业大学Wolfgang Domcke教授的理论化学小组合作。多姆克教授的小组得到了DFG对这项工作的支持。这项研究的更广泛的科学影响将来自于它提供的关于这些物种在早期地球条件下的光稳定性的答案，以及这可能如何影响生命系统的最终化学组成。除了所支持的研究的更广泛的科学影响外，德弗里斯教授还将为他的学生提供复杂的实验技术和最先进的理论方法方面的培训。此外，他的学生将通过与多姆克教授及其团队的合作获得宝贵的国际经验。