Circadian Regulation of Auxin Signal Transduction

生长素信号转导的昼夜节律调节

• 批准号: 0616179
• 负责人: Stacey Harmer
• 金额: $ 37.89万
• 依托单位: University of California-Davis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-15 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0616179&HistoricalAwards=false
• 关键词: Circadian; Regulation; Auxin; Signal; Transduction

Every organism on earth must cope with a constantly changing environment. Animals can deal with environmental stress by moving away from it; however, this is not an option for plants, which are literally rooted in place. Plants have therefore developed sophisticated ways to regulate their physiology and development both in response to their specific growth environment and in anticipation of changes that occur each day due to the earth's rotation on its axis. An unexpected connection has been found between the circadian clock, which regulates many aspects of plant physiology in a time-of-day specific manner, and the plant hormone auxin, which controls many spatial aspects of plant growth and development. A surprising finding is that the circadian clock controls at least some plant responses to the hormone auxin: plants respond differently to auxin when it is administered at different times of day. In the current project, the connection between the circadian clock and auxin responses will be investigated using genetic, genomic, and advanced imaging techniques. This research will help determine 1) whether aspects of auxin responses such as directional growth are also under clock regulation, 2) in which plant organs clock regulation of auxin responses occurs, and 3) the molecular basis of clock regulation of auxin responses. Fundamental insights into how two important regulatory pathways, the circadian clock and auxin signaling, interact with each other are expected. This information will be of great interest to scientists studying both normal plant development and plant responses to environmental stresses, with possible future applications in optimizing growth of crop plant species in variable environments. In addition, the work outlined in this proposal will provide valuable hands-on training for students at the high school, college, graduate, and post-graduate levels. Furthermore, research findings will be presented to high school students, teachers and undergraduates in an effort to promote the understanding and support of science by the general public.

地球上的每一种生物都必须科普不断变化的环境。 动物可以通过远离环境来应对环境压力;然而，这对植物来说不是一个选择，因为植物实际上是扎根在原地的。 因此，植物已经发展出复杂的方式来调节它们的生理和发育，以响应它们特定的生长环境，并预期由于地球绕其轴旋转而每天发生的变化。 在生物钟和植物激素生长素之间发现了一种意想不到的联系，生物钟以特定的方式调节植物生理学的许多方面，而植物激素生长素控制植物生长和发育的许多空间方面。 一个令人惊讶的发现是，生物钟至少控制了植物对激素生长素的一些反应：当在一天中的不同时间施用生长素时，植物对生长素的反应不同。 在目前的项目中，生物钟和生长素反应之间的联系将使用遗传学，基因组学和先进的成像技术进行研究。 这项研究将有助于确定1）生长素反应的各个方面，如定向生长，是否也受到时钟调节，2）生长素反应的时钟调节发生在植物器官中，以及3）生长素反应时钟调节的分子基础。两个重要的调控途径，生物钟和生长素信号，如何相互作用的基本见解预计。 这些信息将对研究正常植物发育和植物对环境胁迫的反应的科学家产生极大的兴趣，并可能在未来应用于优化作物物种在可变环境中的生长。 此外，本提案中概述的工作将为高中、大学、研究生和研究生级别的学生提供宝贵的实践培训。此外，研究结果将介绍给高中生，教师和大学生，以促进公众对科学的理解和支持。