Vibrational, Orientational, and Conformational Dynamics of Molecules in Solution

溶液中分子的振动、取向和构象动力学

• 批准号: 0616575
• 负责人: Andrei Tokmakoff
• 金额: $ 52.82万
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2009-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0616575&HistoricalAwards=false
• 关键词: Vibrational; Orientational; Conformational; Dynamics; Molecules

In this award, funded by the Experimental Physical Chemistry Program of the Chemistry Division, Prof. Andrei Tokmakoff of the Chemistry Department of the Massachusetts Institute of Technology and his graduate student colleagues will study the vibrational orientational and conformational dynamics of biomolecules in solution with two-dimensional infrared (2D-IR) spectroscopy. The ultimate goal of this research is to develop new tools with which to study protein structure and dynamics. Besides the broader scientific impacts of the research being supported, the research students working on these projects will gain experience with advanced laser techniques. Prof. Tokmakoff also maintains a clearinghouse of 2D-IR data on his website, and his course materials are made available through MIT's OpenCourseWare initiative.

在这个由化学系实验物理化学计划资助的奖项中，马萨诸塞州理工学院化学系的Andrei Tokmakoff教授和他的研究生同事将利用二维红外（2D-IR）光谱研究溶液中生物分子的振动取向和构象动力学。 这项研究的最终目标是开发研究蛋白质结构和动力学的新工具。 除了支持研究的更广泛的科学影响外，从事这些项目的研究生还将获得先进激光技术的经验。 Tokmakoff教授还在他的网站上维护了一个2D-IR数据交换所，他的课程材料可以通过麻省理工学院的开放式课程计划获得。