Allergien und Lungenerkrankungen im Erwachsenenalter. Beitrag der deutschen Kohorten Hamburg und Erfurt zum Internationalen Projekt zu Atemwegserkrankungen

成人过敏和肺部疾病。

• 批准号: 179996868
• 负责人: Professor Dr. Joachim Heinrich, Ph.D.
• 金额: --
• 依托单位: Pneumologisches Forschungsinstitut
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2010
• 资助国家: 德国
• 起止时间: 2009-12-31 至 2012-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/179996868?language=en
• 关键词: Allergien; und; Lungenerkrankungen; im; Erwachsenenalter.

The European Community Respiratory Health Survey (ECRHS) is a follow-up study on respiratory health, in particular asthma, allergy and lung function in the general population of adults from more than 20 countries in Europe and some other parts of the world. In Germany a random sample of 20-44 year old adults from Erfurt and Hamburg were examined first of all in the baseline study (ECRHS-I; 1990-1992) and then in the follow-up study (ECRHS-II; 2000-2002). The ECRHS is the only European study providing comprehensive data on respiratory health. It has led to the standardisation of epidemiological research methods of adult asthma and respiratory health. Additionally, the results provided information relevant for programme initiatives in many countries.The 20-year follow-up in the involved countries is supposed to analyse the temporal shift of asthma, allergy and lung function, as well as the association with new risk factors. The objectives of the follow-up are: (i) to describe the long-term development of asthma, rhinitis and sensitisation to allergens and to identify their environmental and genetic determinants; (ii) to quantify lung function decline and the incidence of COPD and their determinants; (iii) to describe the changes in asthma treatment on population and individual level and their influence on the prevalence of asthma symptoms.The German participation in the international follow-up study (ECRHS III) renders it possible to perform respiratory health research in adults on an internationally competetive level.

欧洲共同体呼吸健康调查(ECRHS)是一项关于来自欧洲和世界其他地区20多个国家的普通成年人的呼吸健康，特别是哮喘、过敏和肺功能的后续研究。在德国，首先在基线研究(ECRHS-I；1990-1992年)和后续研究(ECRHS-II；2000-2002年)中对埃尔福特和汉堡的20-44岁成年人进行了随机抽样检查。ECRHS是唯一一项提供有关呼吸健康的全面数据的欧洲研究。它导致了成人哮喘和呼吸道健康流行病学研究方法的标准化。此外，研究结果还为许多国家的方案倡议提供了相关信息。在有关国家进行的20年跟踪调查应分析哮喘、过敏和肺功能的时间变化，以及与新的风险因素的关系。跟进的目标是：(I)描述哮喘、鼻炎和对过敏原的敏感性的长期发展，并确定它们的环境和遗传决定因素；(Ii)量化肺功能下降和COPD的发病率及其决定因素；(Iii)描述哮喘治疗在人群和个人水平上的变化及其对哮喘症状患病率的影响。德国参与国际后续研究(ECRHS III)使在国际竞争水平上进行成人呼吸健康研究成为可能。