GOALI: Investigation of a Sulfuric Acid-Free Route to Methacrylates Using Homogeneous Catalysts in Aqueous Solution.

教授大卫泰勒，化学系，俄勒冈州大学（UO），是由无机，生物无机和有机化学计划之间的合作研究支持泰勒研究小组在UO和研究人员在Rohm和Hass的发展硫酸无方法合成甲基丙烯酸酯。UO拟议研究的主要目标是开发一种可行的均相催化工艺，该工艺涉及拟议的甲基丙烯酸酯无硫酸工业合成中的关键反应。目前的工业方法使用硫酸，每千克甲基丙烯酸酯产物产生约2.5千克硫酸氢铵。硫酸氢铵的处理和处置不仅导致更高的产品成本，而且导致能源浪费、原材料损失和对环境的不必要影响。成功的无硫酸工艺的开发将是“绿色化学”在主要工业过程中令人印象深刻的应用。Rohm和哈斯的工业合作者将在更大规模上研究俄勒冈州大学在实验室规模上开发的成功的无硫酸反应，他们还将研究如何联合收割机各种催化反应，以提供新的无硫酸工艺生产甲基丙烯酸甲酯和相关产品。为了加强研究生的教育和专业发展，UO化学系与各种合作伙伴，包括当地和区域行业，当地K-12学校系统以及众多区域学院和大学合作的历史。与Rohm和哈斯研究人员的会议和电话会议，以及对Rohm和哈斯实验室的长期访问，提供实际的工业经验，将使学生了解学术研究实验室中开发的化学如何转化为大规模的制造过程。这种工业接触将使他们在现实世界中具有明显的优势。代表性不足的群体将在参与这项资助支持的研究的研究生和本科生观众中占有一席之地。

Professor David Tyler, Department of Chemistry, University of Oregon (UO), is supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program for a collaborative study between the Tyler research group at UO and researchers at Rohm and Hass on the development of a sulfuric acid-free method for the synthesis of methacrylates. The primary goal of the proposed research at UO is to develop a viable, homogeneously catalyzed process involving a key reaction in a proposed sulfuric acid-free industrial synthesis of methacrylates. The current industrial method uses sulfuric acid and generates about 2.5 kg of ammonium hydrogen sulfate per kg of methacrylate product. The treatment and disposal of the ammonium hydrogen sulfate contribute not only to higher product costs but also to wasted energy, raw material loss, and an unnecessary impact on the environment. The development of a successful sulfuric acid-free process would be an impressive application of "green chemistry" to a major industrial process. A successful sulfuric acid-free reaction developed on a laboratory scale at the University of Oregon will be studied on a larger scale by industrial collaborators at Rohm and Haas, who will also investigate how to combine various catalyzed reactions to give new sulfuric acid-free processes for the production of methyl methacrylate and related products. For the purpose of enhancing the education and professional development of graduate students, the Chemistry Department at UO has a history of working collaboratively with a variety of partners including local and regional industries, local K-12 school systems, and numerous regional colleges and universities. Meetings and teleconferences with researchers at Rohm and Haas and significantly long visits to the Rohm and Haas labs giving hands-on industrial experience will allow students to learn how chemistry developed in academic research labs is translated into large-scale manufacturing processes. This industrial exposure will give them a distinct edge in the practical world. Underrepresented groups will have a strong presence in the graduate and undergraduate student audience that participates in the research supported by this grant.