MRI: Acquisition of an NMR Spectrometer to Maintain Active Undergraduate Education and Research Programs

MRI：购买 NMR 波谱仪以维持活跃的本科教育和研究项目

• 批准号: 0722178
• 负责人: Justin Miller
• 金额: $ 34.2万
• 依托单位: Hobart and William Smith Colleges
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0722178&HistoricalAwards=false
• 关键词: MRI; Acquisition; NMR; Spectrometer; Maintain

With this award from the Major Research Instrumentation program (MRI), the Department of Chemistry at Hobart and William Smith Colleges will acquire a 400 MHz nuclear magnetic resonance (NMR) spectrometer. The NMR spectrometer will be utilized to elucidate the structure of molecules during organic synthesis including the synthesis of 1) potential anticancer chemotherapeutics and other peptidic bioconjugates, 2) novel organometallic molecular wire candidates for nanoscale devices and 3) biologically active nitrogen heterocycles. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The requested NMR spectrometer will be used to characterize products, identify unknown materials, and determine the three-dimensional geometry of complex structures

霍巴特学院和威廉·史密斯学院的化学系将从主要研究仪器计划(MRI)获得这一奖项，从而获得一台400 MHz的核磁共振(核磁共振)光谱仪。核磁共振波谱仪将用于阐明有机合成过程中的分子结构，包括1)潜在的抗癌化疗药物和其他多肽生物偶合物的合成，2)用于纳米器件的新型有机金属分子线的合成，以及3)生物活性氮杂环的合成。核磁共振波谱是化学家用来阐明分子结构的最有力的工具之一。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。所要求的核磁共振光谱仪将用于表征产品，识别未知材料，并确定复杂结构的三维几何形状