Acquisition of a Cyber-enabled High Performance Electron Impact Mass Spectrometer

在化学研究仪器和设施多用户仪器获取(CRIF-MU)计划的支持下，加州大学伯克利分校化学系将购买一台配备固体探头和气相色谱仪的网络化高性能电子撞击扇形质谱仪。该设备将加强以下领域的研究：1)化学计量和催化有机金属反应的结构和机理研究；2)合成具有生物活性的复杂候选药物和天然产物；3)合成具有生物活性的天然产物；4)合成高氧化态和低氧化态过渡金属配合物；5)开发复杂天然产物的新合成方法，以及苯系物、士的宁和低聚环戊二烯金属的合成。质谱仪(MS)是一种用于探测大量有机、生物有机和有机金属分子的内部结构细节和获得其分子组成的技术。它是发展最快、使用最广泛的分析仪器技术之一。正因为如此，让本科生和研究生接触这项技术是很重要的。研究生、本科生暑期学生和博士后研究人员将使用该仪器进行研究。此外，这台质谱仪将启用网络，使用户能够远程运行样品，并通过“课堂化学”倡议扩大接触包括地区高中在内的校外用户。

With support from the Chemistry Research Instrumentation and Facilities Multiuser Instrument Acquisition (CRIF-MU) Program, the Department of Chemistry at the University of California Berkeley will purchase a cyber-enabled high performance electron impact sector mass spectrometer equipped with a solids probe and a gas chromatograph. This equipment will enhance research in a number of areas including 1) structural and mechanistic investigations of stoichiometric and catalytic organometallic reactions; 2) synthesis of complex, bioactive drug candidates and natural products; 3) the synthesis of biologically active natural products; 4) the synthesis of high and low oxidation-state transition-metal complexes; 5) development of new synthetic methodology for complex natural products and the synthesis of phenylenes, strychnine and oligocyclopentadienyl metals. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. It is one of the fastest growing and most widely used analytical instrumentation techniques. Because of this, it is important for undergraduate and graduate students to be exposed to the technique. Graduate students, undergraduate summer students and postdoctoral researchers will use this instrument for their research. Furthermore, this mass spectrometer will be cyber-enabled to allow users to remotely run samples and broaden the access to off-campus users including area high schools via the "Chemistry in the Classroom" initiative.