Acquisition of an EPR spectrometer for cyber-enabled research and education

该奖项由2009年《美国复苏和再投资法案》(Public Law 111-5)资助。在化学研究仪器和设施多用户计划(CRIF：MU)的资助下，波士顿大学的John E.Straub教授和他的同事Sean J.Elliott将获得一台具有低温能力的电子顺磁共振(EPR)光谱仪，以支持由波士顿大学的Caradonna、Elliott、Doerrer和Liu教授以及波士顿学院的Armstrong和塔夫茨大学的Rybak-Akimova教授进行的无机和生物无机研究。该光谱仪将支持以下方面的研究和教学：基于铁的烷烃活化；高氧化态铁、铜和钴的研究；多血红素细胞色素；金属酶的机理研究；光合作用过程的模型；以及一般无机机制。网络使能将教育经验扩展到附近的机构，如费尔菲尔德大学、伊曼纽尔学院和马萨诸塞大学达特茅斯分校。EPR光谱仪产生关于分子的分子和电子结构的信息。它还可以用来获得有关自由基的寿命和身份的信息，自由基是一种寿命较短的物种，通常对启动肿瘤生长和/或各种化学反应至关重要。这些研究将在许多领域产生影响，从化学到材料和生物化学。该仪器将成为教学和研究不可或缺的一部分。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), Professor John E. Straub and colleague Sean J. Elliott from Boston University will acquire an electron paramagnetic resonance (EPR) spectrometer with cryogenic capability to support inorganic and bioinorganic research carried out by the research groups of Professors Caradonna, Elliott, Doerrer, and Liu at BU, as well as Armstrong from Boston College and Rybak-Akimova from Tufts University. This spectrometer will support research and education in iron-based alkane activation; studies of high-oxidation states iron, copper and cobalt; multi-heme cytochromes; mechanistic studies of metalloenzymes; models for photosynthetic processes; and general inorganic mechanisms. Cyber-enabling will extend the educational experience to nearby institutions such as Fairfield University, Emmanuel College, and the University of Massachusetts-Dartmouth.An EPR spectrometer yields information on the molecular and electronic structure of molecules. It may also be used to obtain information about the lifetimes and identities of free radicals, short-lived species that are often essential for the initiation of tumor growth and/or a variety of chemical reactions. These studies will have an impact in a number of areas, from chemistry to materials and biological chemistry. This instrument will be an integral part of teaching as well as research.