Biomesh: A Digital Resource Collection at the Biology-Engineering Interface

Biomesh：生物工程接口的数字资源集合

• 批准号: 0743460
• 负责人: Elizabeth Dumont
• 金额: $ 98.27万
• 依托单位: University of Massachusetts Amherst
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0743460&HistoricalAwards=false
• 关键词: Biomesh; Digital; Resource; Collection; Biology

The University of Massachusetts Amherst is awarded a grant to develop a shared digital resource collection of finite element models of biological systems. Finite element analysis (FEA) is a computer-based technique for predicting the physical behavior of engineered products based on fundamental principles of mechanics. FEA has revolutionized engineering by allowing the design and optimization of high quality, complex products to occur completely within a digital environment. Now biologists are beginning to use FEA to understand the biomechanical behavior of biological organs, tissues and even cells. FEA has the ability to transform the way that biologists approach problems in areas ranging from functional morphology to paleobiology, developmental biology and cellular mechanics. In addition to finite element models, this resource collection will include an integrated set of web-enabled ontologies for sharing finite element modeling metadata, knowledge and mechanical property values of biological materials, interactive software tools for visualizing FEA models and results, FEA utilities supporting the development of biological finite element models, and a threaded discussion. On a broader scale, this project will capitalize on the visual appeal of FEA to inform the public's perception and understanding of the fundamental integration of biological and engineering sciences. This will be accomplished by developing fresh and exciting educational resources for use in the K-12 classroom and by contributing to college-level courses that use computational tools to teach abstract biological concepts.

马萨诸塞大学阿默斯特分校获得一笔赠款，用于开发生物系统有限元模型的共享数字资源库。有限元分析(FEA)是一种基于计算机的技术，根据力学的基本原理预测工程产品的物理行为。有限元分析使高质量、复杂产品的设计和优化完全在数字环境中进行，从而为工程带来了革命性的变化。现在，生物学家开始使用有限元分析来了解生物器官、组织甚至细胞的生物力学行为。FEA有能力改变生物学家处理从功能形态到古生物学、发育生物学和细胞力学等领域问题的方式。除了有限元模型，这一资源集合还将包括一套集成的网络本体，用于共享生物材料的有限元建模元数据、知识和机械属性值、用于可视化有限元模型和结果的交互式软件工具、支持生物有限元模型开发的有限元实用工具，以及线程化讨论。在更广泛的范围内，这个项目将利用有限元分析的视觉吸引力，让公众了解生物科学和工程科学的基本整合。这将通过开发新的和令人兴奋的教育资源用于K-12课堂，并通过促进使用计算工具教授抽象生物学概念的大学课程来实现。