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Innnovative functional coatings with transition metal oxides and their antimicrobial and catalytic properties

具有过渡金属氧化物的创新功能涂层及其抗菌和催化性能

基本信息

批准号：
186187002
负责人：
Professor Dr. Cordt Zollfrank
金额：
--
依托单位：
Kinder- und Jugendklinik
依托单位国家：
德国
项目类别：
Research Grants
财政年份：
2011
资助国家：
德国
起止时间：
2010-12-31 至 2015-12-31
项目状态：
已结题

来源：
https://gepris.dfg.de/gepris/projekt/186187002?language=en
关键词：
Innnovative functional coatings transition metal

项目摘要

Composites of transition metal oxides (MoO3 and WO3) represent a new class of important materials that are increasingly being developed for use in research due to their favourable physical and chemical properties. These materials are of particular interest as antimicrobial agents and as catalysts in numerous biological, chemical, biomedical and pharmaceutical applications. In the initial project period, we could distinctly demonstrate that compounds comprising transition metal oxides (e.g. MoO3) are highly efficient materials to permanently prevent colonisation of harmful microorganisms of inanimate surfaces. We reported on the reduction of microbial contamination and biofilm growth on inanimate surfaces with incorporated different crystal structures of MoO3 into the various polymer substrates. Many scientific issues related to the mechanism and the catalytic properties related to the antimicrobial activity arose, which will be addressed in the proposed project period. We could also show that MoO3-TiO2 composite with systematically varied compositions prepared by sol-gel-processing exhibit significant photocatalytic degradation properties. As a further development on the application of transition metal oxides we envision the exploration of the catalytic properties for the degradation of lignocellulosic materials. This will enable a cost efficient and green route to produce low-molecular weight compounds. The first aim of this continuation proposal is to elaborate on the antimicrobial mechanism of molybdenum oxide. We propose that the crystallographic phase and water content in MoO3 strongly influence on the antimicrobial activity. The phase and composition will be varied by adapting the materials processing parameters (e.g. thermal treatment). The antimicrobial properties of the synthesised composites will be evaluated as a function of the crystallographic phase. The second scientific issue is related to the charge density distribution on the modified surfaces which avoid the growth, spread and transfer of the microorganisms. Evaluation of the charge density as a function of the molybdenum oxide particle distribution in materials will be envisioned. Based upon the results on the antimicrobial properties and our observation on the photocatalytic properties, the transition metal oxides will be developed as catalytically active materials for photo and chemically induced degradation reactions. One major work hypothesis is that transition metal oxides and their composites are able to degrade lignocellulosic biopolymer compositions for producing low-molecular weight compounds in an ecological and cost efficient route. The influence of different composite materials of MoO3 on the yield of low-molecular weight compounds and residual biopolymers will be elucidated. We believe that this proposal has a substantial importance for future industrial applications in the area of biomass conversion and as antimicrobial agents.

过渡金属氧化物（MoO 3和WO 3）的复合材料代表了一类新的重要材料，由于其良好的物理和化学性质，这些材料正越来越多地被开发用于研究。这些材料在许多生物、化学、生物医学和制药应用中作为抗微生物剂和催化剂特别令人感兴趣。在项目初期，我们可以清楚地证明，包含过渡金属氧化物（例如MoO 3）的化合物是永久防止无生命表面有害微生物定植的高效材料。我们报道了在无生命表面上的微生物污染和生物膜生长的减少，将不同晶体结构的MoO 3掺入到各种聚合物基质中。与抗菌活性有关的机制和催化特性产生了许多科学问题，这些问题将在拟议项目期间得到解决。我们还可以表明，MoO 3-TiO 2复合材料具有系统的变化组成的溶胶-凝胶-处理表现出显着的光催化降解性能。作为过渡金属氧化物应用的进一步发展，我们设想探索木质纤维素材料的降解催化性能。这将实现成本有效的和绿色的路线来生产低分子量化合物。本延续提案的第一个目的是阐述氧化钼的抗菌机制。我们建议，在MoO 3的晶相和水含量强烈影响的抗菌活性。通过调整材料加工参数（例如热处理），可以改变相态和组成。合成的复合材料的抗微生物性能将作为结晶相的函数进行评价。第二个科学问题与改性表面上的电荷密度分布有关，这避免了微生物的生长、扩散和转移。将设想作为材料中氧化钼颗粒分布的函数的电荷密度的评估。基于抗菌性能的结果和我们对光催化性能的观察，过渡金属氧化物将被开发为光和化学诱导降解反应的催化活性材料。一个主要的工作假设是，过渡金属氧化物和它们的复合材料能够降解木质纤维素生物聚合物组合物，用于以生态和成本有效的途径生产低分子量化合物。将阐明MoO 3的不同复合材料对低分子量化合物和残余生物聚合物的产率的影响。我们相信，这一提议对于生物质转化领域和作为抗微生物剂的未来工业应用具有实质性的重要性。

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Enhancement of the antimicrobial properties of orthorhombic molybdenum trioxide by thermal induced fracturing of the hydrates.

DOI：
10.1016/j.msec.2015.09.069
发表时间：
2016
期刊：
Materials science & engineering. C, Materials for biological applications
影响因子：
0
作者：
S. Shafaei;Daniel Van Opdenbosch;T. Fey;M. Koch;T. Kraus;J. Guggenbichler;C. Zollfrank
通讯作者：
S. Shafaei;Daniel Van Opdenbosch;T. Fey;M. Koch;T. Kraus;J. Guggenbichler;C. Zollfrank

Cellulose acetate‐based composites with antimicrobial properties from embedded molybdenum trioxide particles