Glucose-based block-co-oligomers with mixed alpha/beta configuration

具有混合 α/β 构型的葡萄糖嵌段共聚低聚物

• 批准号: 416720146
• 负责人: Professor Dr. Cordt Zollfrank
• 金额: --
• 依托单位: Professur für Biogene Polymere
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2018
• 资助国家: 德国
• 起止时间: 2017-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/416720146?language=en
• 关键词: Glucose; based; block; co; oligomers

Cellulose and starch (amylose) are the most important polysaccharides and are of paramount significance for manufacturing biogenic materials from renewable resources. Both biopolymers are composed solely of glucose as the monomeric unit (anhydroglucose AGU), which are linearly linked without any branching. The only difference between cellulose and starch is the stereochemical configuration ate the anomeric C1-carbon atom of the AGE. Two AGE in cellulose are linked via a beta-1,4-glycosidic bond, whereas an alpha-1,4-glycosidic bond is found in starch. This results in totally different secondary structures and properties of the two polysaccharides. The aim of the present short project is the synthesis of all-glucose block-co-oligomers (as a proof-of-concept), where on block exhibits an alpha-configuration and the other block the beta-configuration. Form the combination of these compounds with two blocks bearing different structural characteristics, novel biogenic materials are expected. The glucose based oligomers alpha-maltotriose and -tetraose serve as a model compounds for starch, whereas beta-cellotriose und -tetraose are model compounds for cellulose. The chemical structures will be determined. Additionally, material properties such as viscoelastic characteristics will be evaluated.

纤维素和淀粉（直链淀粉）是最重要的多糖，对于从可再生资源中生产生物材料具有至关重要的意义。这两种生物聚合物仅由葡萄糖作为单体单元（脱水葡萄糖AGU）组成，其线性连接而没有任何分支。纤维素和淀粉之间的唯一区别是AGE的异头C1-碳原子的立体化学构型。纤维素中的两个AGE通过β-1，4-糖苷键连接，而在淀粉中发现α-1，4-糖苷键。这导致两种多糖的二级结构和性质完全不同。本短项目的目的是合成全葡萄糖嵌段共聚低聚物（作为概念验证），其中一个嵌段呈现α-构型，另一个嵌段呈现β-构型。将这些化合物与具有不同结构特征的两个嵌段结合起来，有望成为新的生物源材料。基于葡萄糖的低聚物α-麦芽三糖和β-四糖用作淀粉的模型化合物，而β-纤维三糖和β-四糖是纤维素的模型化合物。将确定化学结构。此外，还将评估材料特性，如粘弹性特性。