Dynamic Monitoring and Sensing with Single-Molecule Nanoelectronics

ECS-0802077，“单分子纳米电子学的动态监测和传感”摘要本研究的目的是研究单分子电路中的电子涨落。该方法是实施实时处理算法，可以识别和解释可能导致实际传感器应用的可重现的电子信号。基本的实验平台由单壁碳纳米管电路组成，单个分子已共价连接到该电路上。实验方法是获取和表征从这些设备产生的电子信号，因为连接的分子探测、识别或结合周围环境中的伙伴。这个项目的智力优势是它有效地利用了最近的发现，推动分子规模的电子学立即走向实用的方向。其优点包括，通过适当的处理，来自分子装置的信号可以用于定量测量和照亮复杂的化学过程。该项目的更广泛影响包括开发用于化学传感或低成本生物传感的精密敏感装置，提供新的诊断和研究能力。所有的工作将由研究生和本科生在一个旨在让初级研究人员接触到与未来科学职业相关的问题和技术的培训环境中完成。

ECS-0802077,"Dynamic Monitoring and Sensing with Single Molecule Nanoelectronics"AbstractThe objective of this research is to study electronic fluctuations arising in single molecule circuits. The approach is to implement real-time processing algorithms that can identify and interpret reproducible electronic signals that could lead towards practical sensor applications. The underlying experimental platform is comprised of a single-walled carbon nanotube circuit, to which a single molecule has been covalently attached. The experimental approach is to acquire and characterize electronic signals arising from these devices as the attached molecule probes, recognizes, or binds to partners in the surrounding environment.The intellectual merit of this project is its effective use of recent discoveries to push molecular-scale electronics in a direction of immediate practicality. The merit includes the principle that signals from molecular devices, with appropriate processing, can be used to quantitatively measure and illuminate complex chemical processes.The broader impact of this project includes the development of exquisitely sensitive devices for chemical sensing or low cost biosensing, providing new diagnostic and research capabilities. All of the work will be completed by graduate and undergraduate students in a training environment designed to expose junior researchers to problems and techniques relevant to future careers in science.