MRI: An EPR spectrometer for teaching and research

MRI：用于教学和研究的 EPR 波谱仪

• 批准号: 0821082
• 负责人: Michael Shaw
• 金额: $ 17.39万
• 依托单位: Southern Illinois University at Edwardsville
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0821082&HistoricalAwards=false
• 关键词: MRI; EPR; spectrometer; teaching; research

With this award from the Major Research Instrumentation program (MRI), Michael J. Shaw and colleagues Yun Lu, Eric J. Voss, Paul E. Wanda and Chin-Chuan Wei from Southern Illinois University at Edwardsville upgrade an Electron Paramagnetic Resonance (EPR) spectrometer. This spectrometer will allow a core of users to pursue research in: (1) functionalization of conducting molecular wires, (2) changes in cell membrane fluidity during apoptosis, (3) regulation of reactive species by plants and animals and mechanisms of NO synthesis, (4) efforts to eliminate organic solvents in organic synthesis, (5) Cleavage of DNA by metal-bipyridyl complexes, (6) sol-gel synthesis of variable composition glasses, (7) free radicals in xenon difluoride reactions, and (8) study of porous bimetallic cathodes for lithium-ion batteries.An EPR spectrometer yields information on the molecular and electronic structure of molecules. It may also be used to obtain information about the lifetimes of free radicals, short-lived species that are often essential for the initiation of tumor growth and/or a variety of chemical reactions. These studies will have an impact in a number of areas, such as inorganic chemistry, biochemistry, biology, the environment and battery manufacturing. The spectrometer will also be used as a training tool for the students while generating useful knowledge and serving a broad base of users in Southwestern Illinois.

凭借这项来自重大研究仪器计划（MRI）的奖项，Michael J. Shaw和他的同事Yun Lu、Eric J. Voss、Paul E.来自爱德华兹维尔的南伊利诺伊大学的Wanda和Chin-Chuan Wei升级了电子顺磁共振（EPR）光谱仪。该光谱仪将允许核心用户在以下方面进行研究：（1）传导分子线的功能化，（2）细胞凋亡过程中细胞膜流动性的变化，（3）植物和动物对反应性物种的调节以及NO合成的机制，（4）在有机合成中消除有机溶剂的努力，（5）金属-联吡啶络合物对DNA的切割，（6）溶胶-凝胶合成可变成分玻璃，（7）二氟化氙反应中的自由基，（8）锂离子电池多孔阴极的研究。EPR光谱仪提供分子和分子电子结构的信息。它还可以用于获得有关自由基寿命的信息，自由基是通常对肿瘤生长和/或各种化学反应的起始至关重要的短寿命物质。这些研究将对许多领域产生影响，如无机化学、生物化学、生物学、环境和电池制造。该光谱仪还将被用作学生的培训工具，同时产生有用的知识，并为伊利诺伊州西南部的广泛用户提供服务。