MRI: Aquisition of a Laser Scanning Microscope for Imaging of Eukaryotic Organisms for Research and Teaching

MRI：购买用于研究和教学的真核生物成像激光扫描显微镜

• 批准号: 0821192
• 负责人: Wendy Boss
• 金额: $ 39.45万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0821192&HistoricalAwards=false
• 关键词: MRI; Aquisition; Laser; Scanning; Microscope

A grant has been awarded to North Carolina State University (NCSU) to acquire a confocal laser scanning microscope (CLSM) for research and training. The new CLSM is essential to reveal the biological relevance of ongoing cellular, biochemical and genetic studies at NCSU. None of the CLSMs on campus were capable of the high resolution, high sensitivity, dynamic and fixed-specimen imaging required to monitor and analyze the distribution of low levels of multiple fluorescent compounds in organisms. The new CLSM will be housed in the Cellular Molecular Imaging Facility (CMIF), a University-wide facility that is a focal point for imaging training and research.On-campus training and outreach was constrained by the lack of a state-of-the-art CLSM. The CLSM will have immediate and broad impacts on the training of undergraduates, graduates and post graduates at NCSU as well as undergraduates at near-by colleges who take the NCSU biotechnology imaging course. Furthermore, the CLSM will be used by a diverse group of PIs who provide role models as they mentor undergraduates in independent research and participate in summer REU programs involving students from non-research I and minority universities. The CLSM also will be highlighted during the tours and hands on activities for prospective students and local school children. For example, CMIF is a focal point of the ?Expanding your Horizon? program aimed at attracting 7th grade girls from around the State of North Carolina to a career in science, mathematics and engineering. Therefore, the new CLSM will greatly expand teaching, outreach and research activities at NCSU.

北卡罗来纳州州立大学获得了一笔赠款，用于购买一台共焦激光扫描显微镜，用于研究和培训。新的CLSM对于揭示NCSU正在进行的细胞，生化和遗传研究的生物学相关性至关重要。校园里没有一个CLSM能够实现高分辨率、高灵敏度、动态和固定样本成像，以监测和分析生物体中低水平多种荧光化合物的分布。新的CLSM将被安置在细胞分子成像设施（CMIF），一个大学范围内的设施，是一个成像培训和研究的焦点。校园内的培训和推广受到缺乏最先进的CLSM的限制。CLSM将对NCSU的本科生，研究生和研究生以及参加NCSU生物技术成像课程的附近学院的本科生的培训产生直接和广泛的影响。此外，CLSM将由一组不同的PI谁提供榜样，因为他们在独立的研究指导本科生，并参加夏季REU计划涉及非研究I和少数民族大学的学生使用。在图尔斯参观和为未来的学生和当地学童举办的动手活动中，CLSM也将得到强调。例如，CMIF是一个焦点？拓展您的视野？该计划旨在吸引来自北卡罗来纳州的七年级女生从事科学、数学和工程方面的职业。因此，新的CLSM将大大扩大在NCSU的教学，推广和研究活动。